ArticleEinstein (Sao Paulo, Brazil)
Potentially malignant oral lesions: clinicopathological correlations.
Article in Einstein (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Malignant transformation rate of oral precancerous disorders to oral cancer: systematic review and meta-analysis of the current evidence.Frontiers in oral health · 2025Pooled it
- Clinicopathological characteristics and follow-up outcomes of patients with oral potentially malignant disorders: A 7-year observational cohort study.Scientific reports · 2026Observational
- A Comparative Study of the Treatment of Oral Premalignant Lesions with Surgical Excision and Medical Therapy.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Actinic cheilitis in rural workers: prevalence and associated factors.Einstein (Sao Paulo, Brazil) · 2022Article
- Histological Effects of an Innovative 445 Nm Blue Laser During Oral Soft Tissue Biopsy.International journal of environmental research and public health · 2020Article
- Human papillomavirus in premalignant oral lesions: No evidence of association in a Spanish cohort.PloS one · 2019Article
- Intraoral Potentially Malignant Disorders in a Brazilian Oral Pathology Service: Epidemiological, Clinical, and Histopathological Findings.Journal of oncology · 2018Article
- Importance of Early Detection of Potentially Malignant Lesions in the Prevention of Oral Cancer.Materia socio-medica · 2017Article
- Epidemiological profile and clinical characteristics of oral potentially malignant disorders and oral squamous cell carcinoma: A pilot study in Bidar and Gulbarga Districts, Karnataka, India.Journal of oral and maxillofacial pathology : JOMFPArticle
- A morphological classification for vocal fold leukoplakia.Brazilian journal of otorhinolaryngologyArticle
- Clinicopathological features of oral potentially malignant disorders among tobacco users and nonusers.National journal of maxillofacial surgeryArticle
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Authors and funding
6 authors.
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Abstract
objectiveTo determine the incidence of potentially malignant oral lesions, and evaluate and correlate their clinical and pathological aspects.
methodsThe sample consisted of cases clinically diagnosed as oral leukoplakia, oral erythroplakia, erythroleukoplakia, actinic cheilitis, and oral lichen planus treated at a diagnostic center, between May 2012 and July 2013. Statistical tests were conducted adopting a significance level of 5% (p≤0.05).
resultsOut of 340 patients, 106 (31.2%) had potentially malignant oral lesions; and 61 of these (17.9%) were submitted to biopsy. Actinic cheilitis was the most frequent lesion (37.5%) and the lower lip was the most affected site (49.6%). Among 106 patients in the sample, 48 (45.3%) reported nicotine consumption, 35 (33%) reported alcohol intake and 34 (32.1%) sun exposure while working. When clinical and histopathological diagnoses were compared, oral erythroplakia and atypical ulcer were the lesions that exhibited greater compatibility (100% each).
conclusionIn most cases, clinical and histopathological diagnoses were compatible. An association between the occurrence of erythroplakia, leukoplakia and erythroleukoplakia with smoking was observed. Similarly, an association between actinic cheilitis and sun exposure was noted. Erythroleukoplakia presented the highest malignancy grade in this study. Finally, dental surgeons should draw special attention to diagnosis of potentially malignant oral lesions, choose the best management, and control the lesions to avoid their malignant transformation.
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