Evidence map›Paper›PMID 27074168›Full record

ReviewBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2016

HPV vaccines: a controversial issue?

A F Nicol, C V Andrade, F B Russomano, L L S Rodrigues, N S Oliveira, D W Provance

Open access · goldAbstract readReview
In one paragraph

Review in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Human Papillomavirus and Male Infertility: What Do We Know?International journal of molecular sciences · 2023
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. HPV vaccination discourses and the construction of "at-risk" girls.Canadian journal of public health = Revue canadienne de sante publique · 2018
    Article
  17. A high prevalence of human papillomavirus 16 and 18 co-infections in cervical biopsies from southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

A F NicolLaboratório Interdisciplinar de Pesquisas Médicas, Fiocruz, Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brasil.
C V AndradeInstituto Nacional de Saúde da Mulher, Fiocruz, da Criança e do Adolescente Fernandes Figueira, Rio de Janeiro, RJ, Brasil.
F B RussomanoInstituto Nacional de Saúde da Mulher, Fiocruz, da Criança e do Adolescente Fernandes Figueira, Rio de Janeiro, RJ, Brasil.
L L S RodriguesInstituto de Saúde Coletiva, Universidade Federal do Oeste do Pará, Santarém, PA, Brasil.
N S OliveiraLaboratório Interdisciplinar de Pesquisas Médicas, Fiocruz, Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brasil.
D W ProvanceFiocruz, Centro de Desenvolvimento Tecnológico em Saúde, Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz · BRInstituto Nacional de Saúde · MZHospital Universitário Antônio Pedro · BRUniversidade Federal do Oeste do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Controversy still exists over whether the benefits of the available HPV vaccines outweigh the risks and this has suppressed uptake of the HPV vaccines in comparison to other vaccines. Concerns about HPV vaccine safety have led some physicians, healthcare officials and parents to withhold the recommended vaccination from the target population. The most common reason for not administering the prophylactic HPV vaccines are concerns over adverse effects. The aim of this review is the assessment of peer-reviewed scientific data related to measurable outcomes from the use of HPV vaccines throughout the world with focused attention on the potential adverse effects. We found that the majority of studies continue to suggest a positive risk-benefit from vaccination against HPV, with minimal documented adverse effects, which is consistent with other vaccines. However, much of the published scientific data regarding the safety of HPV vaccines appears to originate from within the financially competitive HPV vaccine market. We advocate a more independent monitoring system for vaccine immunogenicity and adverse effects to address potential conflicts of interest with regular systematic literature reviews by qualified individuals to vigilantly assess and communicate adverse effects associated with HPV vaccination. Finally, our evaluation suggests that an expanded use of HPV vaccine into more diverse populations, particularly those living in low-resource settings, would provide numerous health and social benefits.

Indexed as

VaccinationFemaleHumansMalePapillomavirus InfectionsPapillomavirus VaccinesPapillomavirus Vaccines

Identifiers

PMID27074168
PMCPMC4830027
OpenAlexW2314847570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.