Evidence map›Paper›PMID 27074162›Full record

ArticlePLoS neglected tropical diseases2016

Identification and Genomic Analysis of a Novel Group C Orthobunyavirus Isolated from a Mosquito Captured near Iquitos, Peru.

Todd J Treangen, George Schoeler, Adam M Phillippy, Nicholas H Bergman, Michael J Turell

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification of NeotropicalTropical medicine and infectious disease · 2023
    Article
  4. Article
  5. Proactive preparedness for Cat Que virus: AnThe Indian journal of medical research · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Todd J TreangenNational Biodefense Analysis and Countermeasures Center, Frederick, Maryland, United States of America.
George SchoelerDepartment of Entomology, U. S. Naval Medical Research Unit No. 6, Callao, Peru.
Adam M PhillippyNational Biodefense Analysis and Countermeasures Center, Frederick, Maryland, United States of America.
Nicholas H BergmanNational Biodefense Analysis and Countermeasures Center, Frederick, Maryland, United States of America.
Michael J TurellVirology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America.
Naval Medical Research Unit Six · PEUnited States Army Medical Research Institute of Infectious Diseases · US

Funding

Single-molecule sequence assembly and analysisZIAHG200398 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI PHILLIPPY, ADAM · 2016 to 2025
$15.9M
6 · The paper itself

Abstract

Group C orthobunyaviruses are single-stranded RNA viruses found in both South and North America. Until very recently, and despite their status as important vector-borne human pathogens, no Group C whole genome sequences containing all three segments were available in public databases. Here we report a Group C orthobunyavirus, named El Huayo virus, isolated from a pool of Culex portesi mosquitoes captured near Iquitos, Peru. Although initial metagenomic analysis yielded only a handful of reads belonging to the genus Orthobunyavirus, single contig assemblies were generated for L, M, and S segments totaling over 200,000 reads (~0.5% of sample). Given the moderately high viremia in hamsters (>107 plaque-forming units/ml) and the propensity for Cx. portesi to feed on rodents, it is possible that El Huayo virus is maintained in nature in a Culex portesi/rodent cycle. El Huayo virus was found to be most similar to Peruvian Caraparu virus isolates and constitutes a novel subclade within Group C.

Indexed as

Genome, ViralAnimalsChlorocebus aethiopsCricetinaeCulexDNA, ViralGenomicsHumansOrthobunyavirusPeruPhylogenyRNA, ViralSequence Analysis, DNAVero CellsDNA, ViralRNA, Viral

Identifiers

PMID27074162
PMCPMC4830577
OpenAlexW2342267335

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.