SynthesisPloS one2016
An Estimate of the Incidence of Prostate Cancer in Africa: A Systematic Review and Meta-Analysis.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prostate cancer screening and associated factors in Ethiopia: a systematic review and meta-analysis.BMC cancer · 2026Pooled it
- Burden, clinical characteristics, and management patterns of prostate cancer in Nigeria: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Estimating the incidence of breast cancer in Africa: a systematic review and meta-analysis.Journal of global health · 2018Pooled it
- Multiparametric MRI findings, PI-RADS scores, and gleason scores in prostate cancer patients at Kumasi, Ghana: a cross-sectional analysis.BMC medical imaging · 2026Article
- Prostate Cancer Screening in Somalia: A Perspective on Addressing a Critical Gap in Early Detection.Research and reports in urology · 2026Article
- Hemozoin-induced immunomodulation and prostate carcinogenesis: mechanisms and implications.Frontiers in oncology · 2026Review
- Correlating Histological Results and Total Serum Levels of the Prostate-Specific Antigen Among Patients in Southwestern Uganda.Prostate cancer · 2026Article
- Evaluating a Behavioural Theory-Based Board Game (S-S-LIBOG) Against Traditional Health Talk (HT) in Prostate Cancer Education: Findings from a Quasi-Experimental Study, Plus Introducing 17 Other S-S-LIBOGs.Healthcare (Basel, Switzerland) · 2025Article
- Facilitators of, and barriers to, prostate cancer screening uptake: A descriptive phenomenological study of adult men in Namibia.BMC urology · 2025Article
- Vitamins in the Pathogenesis of Prostate Cancer: Implications for Prevention and Therapeutic Support.International journal of molecular sciences · 2025Review
- Correlation of Prostate-Specific Antigen (PSA), Prostate Volume, and Histology in Ugandan Males.Cureus · 2025Article
- Advancing Prostate Cancer Diagnostics: A ConvNeXt Approach to Multi-Class Classification in Underrepresented Populations.Bioengineering (Basel, Switzerland) · 2025Article
- Supraclavicular nodal metastasis at primary staging of prostate cancer usingEJNMMI reports · 2025Article
- The Role of Immunohistochemistry for AMACR/p504s and p63 in Distinguishing Prostate Cancer from Benign Prostate Tissue Samples in Botswana.Research and reports in urology · 2025Article
- Prostate Cancer Among Patients Presenting with Obstructive Lower Urinary Tract Symptoms at a Tertiary Hospital in South Western Uganda.Research and reports in urology · 2025Article
- High body mass index increases the risk for prostate cancer and high Gleason score in northern Tanzania: data from prostate cancer screening.Ecancermedicalscience · 2025Article
- Barriers and sources of information in prostate cancer screening at a South African hospital.Journal of public health in Africa · 2025Article
- Unmasking Elevated PSA: Prevalence and Modifiable Risk Factors in Men Aged ≥ 40 Years Attending Kabutare District Hospital in Rwanda.Research and reports in urology · 2025Article
- Genetic and biological drivers of prostate cancer disparities in Black men.Nature reviews. Urology · 2024Review
- Improving cancer incidence evaluation through local government area matching: a study of the Edo-Benin cancer registry in Nigeria.BMC public health · 2024Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProstate cancer (PCa) is rated the second most common cancer and sixth leading cause of cancer deaths among men globally. Reports show that African men suffer disproportionately from PCa compared to men from other parts of the world. It is still quite difficult to accurately describe the burden of PCa in Africa due to poor cancer registration systems. We systematically reviewed the literature on prostate cancer in Africa and provided a continent-wide incidence rate of PCa based on available data in the region.
methodsA systematic literature search of Medline, EMBASE and Global Health from January 1980 to June 2015 was conducted, with additional search of Google Scholar, International Association of Cancer Registries (IACR), International Agency for Research on Cancer (IARC), and WHO African region websites, for studies that estimated incidence rate of PCa in any African location. Having assessed quality and consistency across selected studies, we extracted incidence rates of PCa and conducted a random effects meta-analysis.
resultsOur search returned 9766 records, with 40 studies spreading across 16 African countries meeting our selection criteria. We estimated a pooled PCa incidence rate of 22.0 (95% CI: 19.93-23.97) per 100,000 population, and also reported a median incidence rate of 19.5 per 100,000 population. We observed an increasing trend in PCa incidence with advancing age, and over the main years covered.
conclusionEffective cancer registration and extensive research are vital to appropriately quantifying PCa burden in Africa. We hope our findings may further assist at identifying relevant gaps, and contribute to improving knowledge, research, and interventions targeted at prostate cancer in Africa.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.