Evidence map›Paper›PMID 27073748›Full record

ReviewCurrent emergency and hospital medicine reports

A Guide to Pain Assessment and Management in the Neonate.

Norina Witt, Seth Coynor, Christopher Edwards, Hans Bradshaw

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Current emergency and hospital medicine reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04596137 (Kangaroo Care Reduces Infant Pain Caused By Vaccination), which is not on this map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
39.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04596137 nacompletednot on this map

Kangaroo Care Reduces Infant Pain Caused By Vaccination

TypeinterventionalSponsorEskisehir Osmangazi UniversityRan2016 to 2017Enrolled128ConditionsInfant, Pain, Kangaroo Mother Care, NursingArmsİnfant pain management
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 241 citations in OpenAlex.

  1. The analgesic effects of human milk odor in preterm neonates: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Pooled it
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  3. Analgesia for retinopathy of prematurity screening: A systematic review.Pain practice : the official journal of World Institute of Pain · 2022
    Pooled it
  4. Impact of breast milk on cortical pain response in newborns during the heel prick procedure: a randomized controlled trial.Journal of perinatology : official journal of the California Perinatal Association · 2024
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Norina WittDepartment of Pediatrics, The University of Arizona, PO Box 245073, Tuscon, 85724 AZ USA.
Seth CoynorDepartment of Pediatrics, The University of Arizona, PO Box 245073, Tuscon, 85724 AZ USA.
Christopher EdwardsDepartments of Pediatrics and Emergency Medicine, The University of Arizona, PO Box 245057, Tucson, 85724-5057 AZ USA ; College of Pharmacy, The University of Arizona, Department of Pharmacy Services, Banner-University Medical Center, PO Box 210202, Tucson, AZ USA.
Hans BradshawDepartments of Pediatrics and Emergency Medicine, The University of Arizona, PO Box 245057, Tucson, 85724-5057 AZ USA.
University of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Newborn infants experience acute pain with various medical procedures. Evidence demonstrates that controlling pain in the newborn period is beneficial, improving physiologic, behavioral, and hormonal outcomes. Multiple validated scoring systems exist to assess pain in a neonate; however, there is no standardized or universal approach for pain management. Healthcare facilities should establish a neonatal pain control program. The first step is to minimize the total number of painful iatrogenic events when possible. If a procedure cannot be avoided, a tiered approach to manage pain using environmental, non-pharmacologic, and pharmacologic modalities is recommended. This systematic approach should decrease acute neonatal pain, poor outcomes, and provider and parent dissatisfaction.

Indexed as

AcetaminophenBreastfeedingFentanylGlucose and sucroseKetamineMorphineNeonatalPain managementTopical and local anesthetics

Identifiers

PMID27073748
PMCPMC4819510
OpenAlexW2293237290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.