Evidence map›Paper›PMID 27073734›Full record

ReviewWorm

Neural circuit rewiring: insights from DD synapse remodeling.

Naina Kurup, Yishi Jin

Open access · bronzeAbstract readReview
In one paragraph

Review in Worm. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. A gene expression atlas of a juvenile nervous system.bioRxiv : the preprint server for biology · 2025
    Article
  2. Review
  3. Review
  4. The epithelial NaCell reports · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. eLife · 2019
    Article
  11. Molecular Architecture of Genetically-Tractable GABA Synapses inFrontiers in molecular neuroscience · 2019
    Article
  12. Intermediate filament accumulation can stabilize microtubules inProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  13. Article
  14. Article
  15. Synaptic remodeling, lessons fromJournal of neurogenetics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Naina KurupNeurobiology Section, Division of Biological Sciences, University of California , San Diego, La Jolla, CA, USA.
Yishi JinNeurobiology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Howard Hughes Medical Institute, University of California, San Diego, La Jolla, CA, USA.
Howard Hughes Medical Institute · USUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nervous systems exhibit many forms of neuronal plasticity during growth, learning and memory consolidation, as well as in response to injury. Such plasticity can occur across entire nervous systems as with the case of insect metamorphosis, in individual classes of neurons, or even at the level of a single neuron. A striking example of neuronal plasticity in C. elegans is the synaptic rewiring of the GABAergic Dorsal D-type motor neurons during larval development, termed DD remodeling. DD remodeling entails multi-step coordination to concurrently eliminate pre-existing synapses and form new synapses on different neurites, without changing the overall morphology of the neuron. This mini-review focuses on recent advances in understanding the cellular and molecular mechanisms driving DD remodeling.

Indexed as

CDK-5CED-3C. elegansDLK-1 MAPKKKdynamicsHBL-1IRX-1kinesinlin-14microtubuleOIG-1transcriptional regulationUNC-30UNC-55

Identifiers

PMID27073734
PMCPMC4805360
OpenAlexW2263324644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.