ReviewPhysiology & behavior2016
Ghrelin: A link between memory and ingestive behavior.
Review in Physiology & behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Pharmacological manipulation of the ghrelin system and alcohol hangover symptoms in heavy drinking individuals: Is there a link?Pharmacology, biochemistry, and behavior · 2018Trial
- Internal-state-dependent control of feeding behavior via hippocampal ghrelin signaling.Neuron · 2024Article
- Postprandial effect of gastrointestinal hormones and gastric activity in patients with irritable bowel syndrome.Scientific reports · 2023Article
- Liver-expressed antimicrobial peptide 2 elevation contributes to age-associated cognitive decline.JCI insight · 2023Article
- Elevated Ghrelin Promotes Hippocampal Ghrelin Receptor Defects in Humanized Amyloid-β Knockin Mice During Aging.Journal of Alzheimer's disease : JAD · 2023Article
- Fasting diets: what are the impacts on eating behaviors, sleep, mood, and well-being?Frontiers in nutrition · 2023Review
- Food cue reactivity: Neurobiological and behavioral underpinnings.Reviews in endocrine & metabolic disorders · 2022Review
- The physiological control of eating: signals, neurons, and networks.Physiological reviews · 2022 · on this mapArticle
- Advances in the Development of Nonpeptide Small Molecules Targeting Ghrelin Receptor.Journal of medicinal chemistry · 2022Review
- Memory and eating: A bidirectional relationship implicated in obesity.Neuroscience and biobehavioral reviews · 2022Review
- Food intake precipitates seizures in temporal lobe epilepsy.Scientific reports · 2021Article
- Activation of ventral CA1 hippocampal neurons projecting to the lateral septum during feeding.Hippocampus · 2021Article
- How Digital Food Affects Our Analog Lives: The Impact of Food Photography on Healthy Eating Behavior.Frontiers in psychology · 2021Review
- Ghrelin Signaling Affects Feeding Behavior, Metabolism, and Memory through the Vagus Nerve.Current biology : CB · 2020Article
- An overview of ghrelinExpert opinion on therapeutic patents · 2020Review
- Ghrelin and Orexin Interact to Increase Meal Size Through a Descending Hippocampus to Hindbrain Signaling Pathway.Biological psychiatry · 2020Article
- The impact of fasting on resting state brain networks in mice.Scientific reports · 2019Article
- The Role of Ghrelin in Regulating Synaptic Function and Plasticity of Feeding-Associated Circuits.Frontiers in cellular neuroscience · 2019Review
- The Cognitive Control of Eating and Body Weight: It's More Than What You "Think".Frontiers in psychology · 2019Review
- Growth hormone secretagogue receptor constitutive activity impairs voltage-gated calcium channel-dependent inhibitory neurotransmission in hippocampal neurons.The Journal of physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Feeding is a highly complex behavior that is influenced by learned associations between external and internal cues. The type of excessive feeding behavior contributing to obesity onset and metabolic deficit may be based, in part, on conditioned appetitive and ingestive behaviors that occur in response to environmental and/or interoceptive cues associated with palatable food. Therefore, there is a critical need to understand the neurobiology underlying learned aspects of feeding behavior. The stomach-derived "hunger" hormone, ghrelin, stimulates appetite and food intake and may function as an important biological substrate linking mnemonic processes with feeding control. The current review highlights data supporting a role for ghrelin in mediating the cognitive and neurobiological mechanisms that underlie conditioned feeding behavior. We discuss the role of learning and memory on food intake control (with a particular focus on hippocampal-dependent memory processes) and provide an overview of conditioned cephalic endocrine responses. A neurobiological framework is provided through which conditioned cephalic ghrelin secretion signals in neurons in the hippocampus, which then engage orexigenic neural circuitry in the lateral hypothalamus to express learned feeding behavior.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.