Evidence map›Paper›PMID 27072391›Full record

ArticleThe British journal of radiology2016

Detection and characterization of breast lesions in a selective diagnostic population: diagnostic accuracy study for comparison between one-view digital breast tomosynthesis and two-view full-field digital mammography.

Eun Young Chae, Hak Hee Kim, Joo Hee Cha, Hee Jung Shin, Woo Jung Choi

Open access · greenAbstract readComparative StudyEvaluation Study
In one paragraph

Article in The British journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Eun Young ChaeDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Hak Hee KimDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Joo Hee ChaDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Hee Jung ShinDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Woo Jung ChoiDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Asan Medical Center · KRUniversity of Ulsan · KRUlsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the performance of one-view digital breast tomosynthesis (DBT) and two-view full-field digital mammography (FFDM) in the detection and characterization of breast lesions in a selective diagnostic population.

methodsA total of 598 breasts of 319 diagnostic patients were prospectively enrolled. Participants underwent bilateral one-view, mediolateral oblique (MLO) DBT and two-view, craniocaudal and MLO FFDM. The sensitivity and specificity of these methods and their classification into correct Breast Imaging-Reporting and Data System (BI-RADS) categories were compared. These methods were also compared in patients subgrouped by mammographic parenchymal density. Receiver operating characteristic (ROC) curve analysis was performed using the probability of cancer scores.

resultsDBT had higher overall sensitivity than FFDM (88.7% vs 80.7%, p = 0.001). Subgroup analyses showed that DBT had significantly higher sensitivity in assessing dense breasts and invasive cancers than FFDM. The BI-RADS category assessment was significantly better for DBT than for FFDM. The differences between the two modalities in specificity (94.1% and 93.2% for FFDM and DBT) were not significant (p = 0.664). The area under the ROC curves using the probability of cancer scores were 0.93 [95% confidence interval (CI), 0.91-0.95] for FFDM and 0.96 (95% CI, 0.94-0.97) for DBT (p = 0.005). ROC curve analysis indicated that most of the increased performance of DBT was due to dense breasts.

conclusionA beneficial effect on the detection and characterization of breast lesions was found for one-view DBT compared with two-view FFDM in a selective diagnostic population. Improvements were especially enhanced in females with dense breasts. These results need to be examined in studies using large-scale consecutive sampling of a diagnostic population. ADVANCES IN KNOWLEDGE: In this study, using selective diagnostic study cases, one-view DBT offered improved reader performance compared with two-view FFDM for detection and characterization of breast cancers.

Indexed as

AdultAgedBreast NeoplasmsFemaleHumansImaging, Three-DimensionalMiddle AgedPatient PositioningPrevalenceRadiographic Image EnhancementReproducibility of ResultsRepublic of KoreaRisk AssessmentRisk FactorsSensitivity and SpecificityTomography, X-Ray Computed

Identifiers

PMID27072391
PMCPMC5258147
OpenAlexW2338833554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.