Evidence map›Paper›PMID 27072368›Full record

ArticleLipids2016

Beef Fat Enriched with Polyunsaturated Fatty Acid Biohydrogenation Products Improves Insulin Sensitivity Without Altering Dyslipidemia in Insulin Resistant JCR:LA-cp Rats.

Abdoulaye Diane, Faye Borthwick, Cletos Mapiye, Payam Vahmani, Rolland C David, Donna F Vine, Michael E R Dugan, Spencer D Proctor

Abstract read
PubMed Publisher
In one paragraph

Article in Lipids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Effects of beef fat enriched withThe British journal of nutrition · 2024
    Article
  3. Article
  4. ncRNAs regulate bovine adipose tissue deposition.Molecular and cellular biochemistry · 2021
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Abdoulaye DianeMetabolic and Cardiovascular Diseases Laboratory, Li Ka Shing Centre for Health Research Innovation, Alberta Diabetes and Mazankowski Institutes, University of Alberta, Edmonton, AB, T6G 2E1, Canada.
Faye BorthwickMetabolic and Cardiovascular Diseases Laboratory, Li Ka Shing Centre for Health Research Innovation, Alberta Diabetes and Mazankowski Institutes, University of Alberta, Edmonton, AB, T6G 2E1, Canada.
Cletos MapiyeDepartment of Animal Sciences, Faculty of AgriSciences, Stellenbosch University, P. Bag X1, Stellenbosch, 7602, South Africa.
Payam VahmaniAgriculture and Agri-Food Canada, Lacombe Research Centre, 6000 C & E Trail, Lacombe, AB, T4L 1W1, Canada.
Rolland C DavidAgriculture and Agri-Food Canada, Lacombe Research Centre, 6000 C & E Trail, Lacombe, AB, T4L 1W1, Canada.
Donna F VineMetabolic and Cardiovascular Diseases Laboratory, Li Ka Shing Centre for Health Research Innovation, Alberta Diabetes and Mazankowski Institutes, University of Alberta, Edmonton, AB, T6G 2E1, Canada.
Michael E R DuganAgriculture and Agri-Food Canada, Lacombe Research Centre, 6000 C & E Trail, Lacombe, AB, T4L 1W1, Canada.
Spencer D ProctorMetabolic and Cardiovascular Diseases Laboratory, Li Ka Shing Centre for Health Research Innovation, Alberta Diabetes and Mazankowski Institutes, University of Alberta, Edmonton, AB, T6G 2E1, Canada. spencer.proctor@ualberta.ca.
University of Alberta · CAAgriculture and Agri-Food Canada · CAStellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main dietary sources of trans fatty acids are partially hydrogenated vegetable oils (PHVO), and products derived from polyunsaturated fatty acid biohydrogenation (PUFA-BHP) in ruminants. Trans fatty acid intake has historically been associated with negative effects on health, generating an anti-trans fat campaign to reduce their consumption. The profiles and effects on health of PHVO and PUFA-BHP can, however, be quite different. Dairy products naturally enriched with vaccenic and rumenic acids have many purported health benefits, but the putative benefits of beef fat naturally enriched with PUFA-BHP have not been investigated. The objective of the present experiment was to determine the effects of beef peri-renal fat (PRF) with differing enrichments of PUFA-BHP on lipid and insulin metabolism in a rodent model of dyslipidemia and insulin resistance (JCR:LA-cp rat). The results showed that 6 weeks of diet supplementation with beef PRF naturally enriched due to flaxseed (FS-PRF) or sunflower-seed (SS-PRF) feeding to cattle significantly improved plasma fasting insulin levels and insulin sensitivity, postprandial insulin levels (only in the FS-PRF) without altering dyslipidemia. Moreover, FS-PRF but not SS-PRF attenuated adipose tissue accumulation. Therefore, enhancing levels of PUFA-BHP in beef PRF with FS feeding may be a useful approach to maximize the health-conferring value of beef-derived fats.

Indexed as

Animal FeedAnimalsCattleDairy ProductsDietary Fats, UnsaturatedDietary SupplementsDisease Models, AnimalDyslipidemiasFatty Acids, UnsaturatedHydrogenationInsulin ResistanceLinseed OilLipidsMalePlant OilsRatsDietary Fats, UnsaturatedFatty Acids, UnsaturatedLinseed OilLipidsPlant OilsSunflower OilTrans Fatty AcidsBeef peri-renal fatFlaxseedInsulin sensitivityJCR ratsPUFA-BHPSunflower-seed

Identifiers

PMID27072368
OpenAlexW2342082871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.