ReviewSports medicine (Auckland, N.Z.)2016
Co-ingestion of Nutritional Ergogenic Aids and High-Intensity Exercise Performance.
Review in Sports medicine (Auckland, N.Z.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Effect of Caffeine and Nitrates Combination on Exercise Performance, Heart Rate and Oxygen Uptake: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Trial
- Supplementation of caffeine and sodium bicarbonate together could not improve performance and performance-related factors in CrossFit participants: a randomized, double-blind, placebo-controlled study.Journal of the International Society of Sports Nutrition · 2023Trial
- A Randomized Controlled Trial of Changes in Fluid Distribution across Menstrual Phases with Creatine Supplementation.Nutrients · 2023Trial
- Effects of Combined Creatine and Sodium Bicarbonate Supplementation on Soccer-Specific Performance in Elite Soccer Players: A Randomized Controlled Trial.International journal of environmental research and public health · 2021Trial
- Short-term co-ingestion of creatine and sodium bicarbonate improves anaerobic performance in trained taekwondo athletes.Journal of the International Society of Sports Nutrition · 2021Trial
- Caffeine and sodium bicarbonate supplementation alone or together improve karate performance.Journal of the International Society of Sports Nutrition · 2019Trial
- Acute Effects of 2S-Hesperidin Supplementation on Performance and External Load in Female Basketball Players.Sports (Basel, Switzerland) · 2026Article
- Which Protein-Based Dietary Supplements Most Effectively Enhance Fat-Free Mass and Strength Gains in Healthy Adults Undergoing Resistance Training? A Network Meta-Analysis.Translational sports medicine · 2026Review
- Longitudinal Changes in Dietary Supplement Use among United States Military Personnel: The US Military Dietary Supplement Use Study.Nutrients · 2024Article
- Pre-Exercise Caffeine and Sodium Bicarbonate: Their Effects on Isometric Mid-Thigh Pull Performance in a Crossover, Double-Blind, Placebo-Controlled Study.Sports (Basel, Switzerland) · 2024Article
- Advances in Understanding the Interplay between Dietary Practices, Body Composition, and Sports Performance in Athletes.Nutrients · 2024Review
- Testosterone and cortisol responses to ß-hydroxy ß-methylbutryate consumption and exercise: A meta-analysis.Food science & nutrition · 2022Review
- Acute effects of beetroot juice and caffeine co-ingestion during a team-sport-specific intermittent exercise test in semi-professional soccer players: a randomized, double-blind, placebo-controlled study.BMC sports science, medicine & rehabilitation · 2022Article
- Effects of a Single Dose of a Creatine-Based Multi-Ingredient Pre-workout Supplement Compared to Creatine Alone on Performance Fatigability After Resistance Exercise: A Double-Blind Crossover Design Study.Frontiers in nutrition · 2022Article
- Acute enteric-coated sodium bicarbonate has negligible effect on anaerobic performance but affects metabolomics and attenuates the gastrointestinal response.Frontiers in physiology · 2022Article
- Prevalence of and Factors Associated with Dietary Supplement Use in a Stratified, Random Sample of US Military Personnel: The US Military Dietary Supplement Use Study.The Journal of nutrition · 2021Article
- Connections between Different Sports and Ergogenic Aids-Focusing on Salivary Cortisol and Amylase.Medicina (Kaunas, Lithuania) · 2021Review
- Effects of Caffeine on Exercise Duration, Critical Velocity, and Ratings of Perceived Exertion During Repeated-Sprint Exercise in Physically Active Men.International journal of exercise science · 2021Article
- Effects of Dietary Supplements on Adaptations to Endurance Training.Sports medicine (Auckland, N.Z.) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many sports involve repeated bouts of high-intensity exercise. High-intensity exercise is compromised, however, by the early onset of exercise-induced fatigue. Metabolic by-products, ion dysbalance and amount of phosphocreatine are considered the main peripheral causes of fatigue during high-intensity exercise. Intake of nutritional ergogenic aids is commonplace to enhance performance of high-intensity exercise by offsetting the potential mechanisms of fatigue. Creatine, probably one of the best known nutritional aids to enhance performance of high-intensity exercise, has convincingly substantiated its ergogenic potential. Although multi-ingredient supplements are now common, the justification for effectiveness is mostly based on observations with single intake of those ingredients. In this narrative review, the main focus is on the evidence of the effect of co-ingestion of ergogenic aids on performance of high intensity exercise for which the single intake has shown beneficial effects on high-intensity performance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.