Evidence map›Paper›PMID 27071649›Full record

ReviewWiley interdisciplinary reviews. RNA2016

SAXS studies of RNA: structures, dynamics, and interactions with partners.

Yujie Chen, Lois Pollack

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Article
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  8. Molecular insights into de novo small-molecule recognition by an intron RNA structure.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
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  11. Article
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  14. Identification of RNA structures and their roles in RNA functions.Nature reviews. Molecular cell biology · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Hierarchical Assembly of Single-Stranded RNA.Journal of chemical theory and computation · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yujie ChenSchool of Applied and Engineering Physics, Cornell University, Ithaca, NY, USA.
Lois PollackSchool of Applied and Engineering Physics, Cornell University, Ithaca, NY, USA.

Funding

RNA folding: from global structure to atomic detailR01GM085062 · NIGMS · CORNELL UNIVERSITY · PI ELBER, RON, POLLACK, LOIS · 2009 to 2017
$2.7M
DNA - DNA interactions with atomic detailR01GM099450 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BAKER, NATHAN A., ONUFRIEV, ALEXEY VLAD · 2012 to 2015
$1.3M
NIGMS NIH HHS R01 GM085062NIGMS NIH HHS R01 GM099450
6 · The paper itself

Abstract

Small-angle X-ray scattering, SAXS, is a powerful and easily employed experimental technique that provides solution structures of macromolecules. The size and shape parameters derived from SAXS provide global structural information about these molecules in solution and essentially complement data acquired by other biophysical methods. As applied to protein systems, SAXS is a relatively mature technology: sophisticated tools exist to acquire and analyze data, and to create structural models that include dynamically flexible ensembles. Given the expanding appreciation of RNA's biological roles, there is a need to develop comparable tools to characterize solution structures of RNA, including its interactions with important biological partners. We review the progress toward achieving this goal, focusing on experimental and computational innovations. The use of multiphase modeling, absolute calibration and contrast variation methods, among others, provides new and often unique ways of visualizing this important biological molecule and its essential partners: ions, other RNAs, or proteins. WIREs RNA 2016, 7:512-526. doi: 10.1002/wrna.1349 For further resources related to this article, please visit the WIREs website.

Indexed as

Nucleic Acid ConformationScattering, Small AngleX-Ray DiffractionRNARNA

Identifiers

PMID27071649
PMCPMC4909577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.