Evidence map›Paper›PMID 27071388›Full record

ArticleIntensive care medicine2016

Withholding and withdrawal of life-sustaining treatments in low-middle-income versus high-income Asian countries and regions.

Jason Phua, Gavin M Joynt, Masaji Nishimura, Yiyun Deng, Sheila Nainan Myatra, Yiong Huak Chan, Nguyen Gia Binh, Cheng Cheng Tan, Mohammad Omar Faruq, Yaseen M Arabi and 9 more

Erratum issuedAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Article
  4. Willingness and Ability to Pay for Critical Care Treatment for Non-COVID Illness during the COVID-19 Pandemic: A Prospective Observational Study in a Tertiary Care Centre in India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  5. Article
  6. Observational
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Planning for a Dignified Death with a Living Will.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
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  14. Article
  15. Article
  16. The Indian Society of Critical Care Medicine Position Statement on the Management of Sepsis in Resource-limited Settings.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  17. Review
  18. Semiotics of ICU Physicians' Views on End-of-life Care and Quality of Dying in a Critical Care Setting: A Qualitative Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  19. Article
  20. Indian Society of Critical Care Medicine and Indian Association of Palliative Care Expert Consensus and Position Statements for End-of-life and Palliative Care in the Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Jason PhuaDivision of Respiratory and Critical Care Medicine, University Medicine Cluster, National University Hospital, National University Health System, Singapore, Singapore.
Gavin M JoyntDepartment of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
Masaji NishimuraEmergency and Critical Care Medicine, University of Tokushima Graduate School, Tokushima, Japan.
Yiyun DengIntensive Care Unit, West China Hospital of Sichuan University, Chengdu, China.
Sheila Nainan MyatraDepartment of Anaesthesia, Critical Care and Pain, Tata Memorial Hospital, Mumbai, India.
Yiong Huak ChanBiostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Nguyen Gia BinhIntensive Care Department, Bach Mai Hospital, Hanoi, Vietnam.
Cheng Cheng TanDepartment of Anaesthesia and Intensive Care, Sultanah Aminah Hospital, Johor Bahru, Malaysia.
Mohammad Omar FaruqDepartment of Critical Care Medicine, BIRDEM General Hospital, Ibrahim Medical College, Dhaka, Bangladesh.
Yaseen M ArabiKing Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Bambang WahjuprajitnoDepartment of Anesthesiology and Reanimation, Faculty of Medicine, University of Airlangga, Dr. Soetomo General Hospital, Surabaya, Indonesia.
Shih-Feng LiuDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Seyed Mohammad Reza HashemianChronic Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung Disease, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Waqar KashifSection of Nephrology, Pulmonary and Critical Care, Department of Medicine, Aga Khan University and Hospital, Karachi, Pakistan.
Dusit StawornPhramongkutklao Hospital, Bangkok, Thailand.
Jose Emmanuel PaloThe Medical City, Pasig City, Philippines.
Younsuck KohDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap Dong Songpa Ku, Seoul, 138-736, South Korea. yskoh@amc.seoul.kr.
ACME Study Investigators
Asian Critical Care Clinical Trials Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the attitudes of physicians towards withholding and withdrawing life-sustaining treatments in intensive care units (ICUs) in low-middle-income Asian countries and regions with those in high-income ones, and to explore differences in the role of families and surrogates, legal risks, and financial considerations between these countries and regions.

methodsQuestionnaire study conducted in May-December 2012 on 847 physicians from 255 ICUs in 10 low-middle-income countries and regions according to the World Bank's classification, and 618 physicians from 211 ICUs in six high-income countries and regions.

resultsAfter we accounted for personal, ICU, and hospital characteristics on multivariable analyses using generalised linear mixed models, physicians from low-middle-income countries and regions were less likely to limit cardiopulmonary resuscitation, mechanical ventilation, vasopressors and inotropes, tracheostomy and haemodialysis than those from high-income countries and regions. They were more likely to involve families in end-of-life care discussions and to perceive legal risks with limitation of life-sustaining treatments and do-not-resuscitate orders. Nonetheless, they were also more likely to accede to families' requests to withdraw life-sustaining treatments in a patient with an otherwise reasonable chance of survival on financial grounds in a case scenario (adjusted odds ratio 5.05, 95 % confidence interval 2.69-9.51, P < 0.001).

conclusionsSignificant differences in ICU physicians' self-reported practice of limiting life-sustaining treatments, the role of families and surrogates, perception of legal risks and financial considerations exist between low-middle-income and high-income Asian countries and regions.

Indexed as

Attitude of Health PersonnelIncomeLife Support SystemsAsiaHumansIntensive Care UnitsPhysiciansCritical careEconomicsEnd-of-life careFamiliesLegalPhysicians

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.