ArticleProceedings of the National Academy of Sciences of the United States of America2016
Ape malaria transmission and potential for ape-to-human transfers in Africa.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45 citing papers in PubMed.
- Hidden hematological, biochemical and immune costs of asymptomatic malaria infections in semi-wild chimpanzees.PLoS pathogens · 2026Article
- Assessment of automated loop-mediated isothermal amplification-(LAMP-)based xenomonitoring for Plasmodium spp. in Anopheles mosquitoes.Malaria journal · 2026Article
- Rodent malaria parasites detected in the invasiveInternational journal for parasitology. Parasites and wildlife · 2025Article
- Bringing to light unnoticed data on the genetic and host diversity of ungulateInternational journal for parasitology. Parasites and wildlife · 2025Article
- Host preference patterns in domestic and wild settings: Insights intoEvolutionary applications · 2024Article
- The Genome of Plasmodium gonderi: Insights into the Evolution of Human Malaria Parasites.Genome biology and evolution · 2024Article
- A chromosomal reference genome sequence for the malaria mosquito,Wellcome open research · 2024Article
- Mosquito-Borne Arboviruses Occurrence and Distribution in the Last Three Decades in Central Africa: A Systematic Literature Review.Microorganisms · 2023Review
- Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa.Journal of public health in Africa · 2023Article
- Role ofProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Myzomyia and Pyretophorus series of Anopheles mosquitoes acting as probable vectors of the goat malaria parasite Plasmodium caprae in Thailand.Scientific reports · 2023Article
- A chromosomal reference genome sequence for the malaria mosquito,Wellcome open research · 2023Article
- A review of Gabonese gorillas and their pathogens: Diversity, transfer and One Health approach to avoid future outbreaks?Frontiers in parasitology · 2023Review
- The ecology and epidemiology of malaria parasitism in wild chimpanzee reservoirs.Communications biology · 2022Article
- Systematic Review on Diversity and Distribution ofPathogens (Basel, Switzerland) · 2022Review
- Molecular Detection and Characterization of Intestinal and Blood Parasites in Wild Chimpanzees (Animals : an open access journal from MDPI · 2021Article
- A universal vaccine candidate against Plasmodium vivax malaria confers protective immunity against the three PvCSP alleles.Scientific reports · 2021Article
- Molecular Identification ofPathogens (Basel, Switzerland) · 2021Article
- Population genomic evidence ofScience advances · 2021Article
- Plasmodium-a brief introduction to the parasites causing human malaria and their basic biology.Journal of physiological anthropology · 2021Review
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18 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Recent studies have highlighted the large diversity of malaria parasites infecting African great apes (subgenus Laverania) and their strong host specificity. Although the existence of genetic incompatibilities preventing the cross-species transfer may explain host specificity, the existence of vectors with a high preference for a determined host represents another possibility. To test this hypothesis, we undertook a 15-mo-long longitudinal entomological survey in two forest regions of Gabon, where wild apes live, at different heights under the canopy. More than 2,400 anopheline mosquitoes belonging to 18 species were collected. Among them, only three species of Anopheles were found infected with ape Plasmodium: Anopheles vinckei, Anopheles moucheti, and Anopheles marshallii Their role in transmission was confirmed by the detection of the parasites in their salivary glands. Among these species, An. vinckei showed significantly the highest prevalence of infection and was shown to be able to transmit parasites of both chimpanzees and gorillas. Transmission was also shown to be conditioned by seasonal factors and by the heights of capture under the canopy. Moreover, human landing catches of sylvan Anopheles demonstrated the propensity of these three vector species to feed on humans when available. Our results suggest therefore that the strong host specificity observed in the Laveranias is not linked to a specific association between the vertebrate host and the vector species and highlight the potential role of these vectors as bridge between apes and humans.
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