Evidence map›Paper›PMID 27070789›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2016

Neutrophil/Lymphocyte Ratio, Serum Endocan, and Nesfatin-1 Levels in Patients with Psoriasis Vulgaris Undergoing Phototherapy Treatment.

Aybala Erek Toprak, Emin Ozlu, Tugba Kevser Uzuncakmak, Emre Yalcınkaya, Sadık Sogut, Ayşe Serap Karadag

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Neutrophils in Psoriasis.Frontiers in immunology · 2019
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aybala Erek ToprakDepartment of Biochemistry, Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey.
Emin OzluDepartment of Dermatology, Kayseri Training and Research Hospital, Kayseri, Turkey.
Tugba Kevser UzuncakmakDepartment of Dermatology, Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey.
Emre YalcınkayaDepartment of Biochemistry, Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey.
Sadık SogutDepartment of Biochemistry, Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey.
Ayşe Serap KaradagDepartment of Dermatology, Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey.
Istanbul Medeniyet University · TRKayseri Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Psoriasis is an autoimmune, inflammatory, and chronic disease. Recent studies have evaluated serum endocan and nesfatin-1 levels in patients with inflammatory disorders. The neutrophil-to-lymphocyte ratio (NLR) is an inflammatory marker currently used in many diseases. The aim of the present study was to evaluate NLR, serum endocan, and nesfatin-1 levels in psoriasis vulgaris before and after narrow-band ultraviolet B (NB-UVB) phototherapy treatment and compared to healthy controls. MATERIAL AND METHODS This study was conducted on a total of 88 cases, 39 of which had psoriasis vulgaris and 49 were healthy volunteers. Thirty-nine psoriasis vulgaris patients underwent NB-UVB phototherapy treatment for 3 months. NLR, serum endocan, and nesfatin-1 levels were measured in all psoriasis patients before and after NB-UVB phototherapy and in the control group. RESULTS Compared with the control group, neutrophil count and NLR were significantly higher (p<0.001) in psoriasis patients before NB-UVB phototherapy. Serum endocan levels were significantly correlated with disease activity before treatment. There was no significant difference in NLR, serum endocan, and nesfatin-1 levels in psoriasis patients before and after NB-UVB phototherapy (p>0.05). CONCLUSIONS The current study shows that NLR was higher in psoriasis vulgaris patients when compared with the control group, whereas serum endocan and nesfatin-1 levels were not significantly different. In addition, NB-UVB phototherapy did not affect NLR, serum endocan, or nesfatin-1 levels. Further larger-scale studies are required on this subject.

Indexed as

AdultBiomarkersCalcium-Binding ProteinsCase-Control StudiesDNA-Binding ProteinsFemaleHumansLymphocytesMaleMiddle AgedNeoplasm ProteinsNerve Tissue ProteinsNeutrophilsNucleobindinsPhototherapyProteoglycansBiomarkersCalcium-Binding ProteinsDNA-Binding ProteinsESM1 protein, humanNeoplasm ProteinsNerve Tissue ProteinsNUCB2 protein, humanNucleobindinsProteoglycans

Identifiers

PMID27070789
PMCPMC4831300
OpenAlexW2340288216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.