ArticlePsychoneuroendocrinology2016
Perceived neighborhood problems are associated with shorter telomere length in African American women.
Article in Psychoneuroendocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 43 citations in OpenAlex.
- Neighborhood built environment, psychosocial stressors, and telomere length of birth parents and their newborns from San Francisco, California.Journal of exposure science & environmental epidemiology · 2026Article
- Neighborhood built environment and leukocyte telomere length among African American adults in the Jackson Heart Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2026Article
- The application of neighborhood area deprivation index to improve health equity across the spectrum of heart failure: a review.Heart failure reviews · 2025Review
- Accelerated molecular aging in socioeconomically disadvantaged neighborhoods: A racial/ethnic comparison.Health & place · 2025Article
- Neighborhood Stressors and Epigenetic Age Acceleration Among Older Americans.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Robust evidence supports a causal link between higher birthweight and longer telomere length: a mendelian randomization study.Frontiers in genetics · 2024Article
- Biological Age Mediates the Effects of Perceived Neighborhood Problems on Heart Failure Risk Among Black Persons.Journal of racial and ethnic health disparities · 2023Article
- Examining the Cross-sectional Association Between Neighborhood Conditions, Discrimination, and Telomere Length in a Predominantly African American Sample.Journal of racial and ethnic health disparities · 2023Article
- Distinct moderating pathways for psychosocial risk and resilience in the association of neighborhood disadvantage with incident heart failure among Black persons.SSM - population health · 2023Article
- Age-related social selectivity: An adaptive lens on a later life social phenotype.Neuroscience and biobehavioral reviews · 2023Review
- Neighborhood disadvantage and biological aging biomarkers among breast cancer patients.Scientific reports · 2022Article
- Integrating Environment and Aging Research: Opportunities for Synergy and Acceleration.Frontiers in aging neuroscience · 2022Review
- Land use mix and leukocyte telomere length in Mexican Americans.Scientific reports · 2021Article
- Article
- Associations between perceived neighborhood environment and cognitive function among middle-aged and older women and men: Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study.Social psychiatry and psychiatric epidemiology · 2020Article
- The relationship between neighborhood socioeconomic deprivation and telomere length: The 1999-2002 National Health and Nutrition Examination Survey.SSM - population health · 2020Article
- Association between telomere length and neighborhood characteristics by race and region in US midlife and older adults.Health & place · 2020Article
- Associations Between Neighborhood Problems and Sexual Behaviors Among Black Men Who Have Sex with Men in the Deep South: The MARI Study.Archives of sexual behavior · 2020Article
- An investigation of racial/ethnic and sex differences in the association between experiences of everyday discrimination and leukocyte telomere length among patients with coronary artery disease.Psychoneuroendocrinology · 2019Article
- Stress and Immunological Aging.Current opinion in behavioral sciences · 2019Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesAfrican Americans (AA) experience higher levels of stress related to living in racially segregated and poor neighborhoods. However, little is known about the associations between perceived neighborhood environments and cellular aging among adult AA. This study examined whether perceived neighborhood environments were associated with telomere length (TL) in AA after adjustment for individual-level risk factors.
methodsThe analysis included 158 women and 75 men AA aged 30-55 years from the Morehouse School of Medicine Study. Relative TL (T/S ratio) was measured from peripheral blood leukocytes using quantitative real-time polymerase chain reaction. Multivariable linear regression models were used to examine the associations of perceived neighborhood social cohesion, problems, and overall unfavorable perceptions with log-TL.
resultsWomen had significantly longer TL than men (0.59 vs. 0.54, p=0.012). After controlling for sociodemographic, and biomedical and psychosocial factors, a 1-SD increase in perceived neighborhood problems was associated with 7.3% shorter TL in women (Mean Difference [MD]=-0.073 (Standard Error=0.03), p=0.012). Overall unfavorable perception of neighborhood was also associated with 5.9% shorter TL among women (MD=-0.059(0.03), p=0.023). Better perceived social cohesion were associated with 2.4% longer TL, but did not reach statistical significance (MD=0.024(0.02), p=0.218). No association was observed between perceived neighborhood environments and TL in men.
conclusionsOur findings suggest that perceived neighborhood environments may be predictive of cellular aging in AA women even after accounting for individual-level risk factors. Additional research with a larger sample is needed to determine whether perceived neighborhood environments are causally related to TL.
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