Evidence map›Paper›PMID 27070153›Full record

ArticlePloS one2016

Relationship between Serum Ferritin Levels and Dyslipidemia in Korean Adolescents.

Young-Eun Kim, Do-Hoon Kim, Yong-Kyun Roh, Sang-Yhun Ju, Yeo-Joon Yoon, Ga-Eun Nam, Hyo-Yun Nam, Jun-Seok Choi, Jong-Eun Lee, Jung-Eun Sang and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  15. Ferritin levels throughout childhood and metabolic syndrome in adolescent stage.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Young-Eun KimDepartment of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
Do-Hoon KimDepartment of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
Yong-Kyun RohDepartment of Family Medicine, Hallym University, College of Medicine, Chunchon, Republic of Korea.
Sang-Yhun JuDepartment of Family Medicine, Catholic University, College of Medicine, Seoul, Republic of Korea.
Yeo-Joon YoonDepartment of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
Ga-Eun NamDepartment of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
Hyo-Yun NamDepartment of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
Jun-Seok ChoiDepartment of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
Jong-Eun LeeDepartment of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
Jung-Eun SangDepartment of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
Kyungdo HanDepartment of Biostatistics, Catholic University College of Medicine, Seoul, Republic of Korea.
Yong-Gyu ParkDepartment of Biostatistics, Catholic University College of Medicine, Seoul, Republic of Korea.
Korea University · KRCatholic University of Korea · KRHallym University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFerritin is associated with various cardiometabolic risk factors such as dyslipidemia, hypertension, obesity, and insulin resistance in adults. We aimed to study the association between serum ferritin levels and dyslipidemia in adolescents, because dyslipidemia is considered an important modifiable cardiovascular risk factor in the young.

methodsWe analyzed 1,879 subjects (1,026 boys and 853 girls) from the 2009-2010 Korean National Health and Nutrition Examination Survey IV. Subjects were categorized into quartiles according to their lipid parameters, which were classified according to age and gender. Those in the highest quartile groups for total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride concentrations were diagnosed as having dyslipidemia. Those in the lowest quartile for high-density lipoprotein cholesterol (HDL-C) values were diagnosed with abnormal levels.

resultsIn boys, total cholesterol, LDL-C, and triglyceride concentrations were significantly correlated with serum ferritin levels. In both boys and girls, serum ferritin levels were negatively associated with HDL-C values, even after adjusting for all covariates. Furthermore, there was no significant correlation between serum ferritin levels and total cholesterol, LDL, and triglyceride concentrations in girls.

conclusionSerum ferritin levels were significantly associated with major dyslipidemia parameters, more prominently in boys than in girls, and this association represents a cardiometabolic risk factor.

Indexed as

AdolescentChildCholesterolCholesterol, HDLCholesterol, LDLCross-Sectional StudiesDyslipidemiasFemaleFerritinsHumansInsulin ResistanceMaleNutrition SurveysRepublic of KoreaRisk FactorsTriglyceridesCholesterolCholesterol, HDLCholesterol, LDLFerritinsTriglycerides

Identifiers

PMID27070153
PMCPMC4829261
OpenAlexW2338200499

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.