Evidence map›Paper›PMID 27070139›Full record

ArticleSleep2016

Nonadherence with Employer-Mandated Sleep Apnea Treatment and Increased Risk of Serious Truck Crashes.

Stephen V Burks, Jon E Anderson, Matthew Bombyk, Rebecca Haider, Derek Ganzhorn, Xueyang Jiao, Connor Lewis, Andrew Lexvold, Hong Liu, Jiachen Ning and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Sleep, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

  1. Management of Obstructive Sleep Apnea in Commercial Motor Vehicle Operators: Recommendations of the AASM Sleep and Transportation Safety Awareness Task Force.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017
    Guideline
  2. Trial
  3. Trial
  4. Tailored Approach to Sleep Health Education (TASHE): a randomized controlled trial of a web-based application.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Long-term health outcomes for patients with obstructive sleep apnea: placing the Agency for Healthcare Research and Quality report in context-a multisociety commentary.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  13. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  14. Review
  15. Obstructive sleep apnea screening, diagnosis, and treatment in the transportation industry.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Stephen V BurksDivision of Social Science, University of Minnesota, Morris, MN.
Jon E AndersonDivision of Science and Math, University of Minnesota, Morris, MN.
Matthew BombykDivision of Social Science, University of Minnesota, Morris, MN.
Rebecca HaiderDivision of Social Science, University of Minnesota, Morris, MN.
Derek GanzhornDivision of Social Science, University of Minnesota, Morris, MN.
Xueyang JiaoDivision of Social Science, University of Minnesota, Morris, MN.
Connor LewisDivision of Science and Math, University of Minnesota, Morris, MN.
Andrew LexvoldDivision of Science and Math, University of Minnesota, Morris, MN.
Hong LiuDivision of Social Science, University of Minnesota, Morris, MN.
Jiachen NingDivision of Social Science, University of Minnesota, Morris, MN.
Alice TollDivision of Science and Math, University of Minnesota, Morris, MN.
Jeffrey S HickmanVirginia Tech Transportation Institute, Blacksburg, VA.
Erin MabryVirginia Tech Transportation Institute, Blacksburg, VA.
Mark BergerPrecision Pulmonary Diagnostics, Houston, TX.
Atul MalhotraDivision of Pulmonary and Critical Care Medicine, School of Medicine, University of California, San Diego, San Diego, CA.
Charles A CzeislerDivision of Sleep Medicine and Circadian Disorders, Department of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA.
Stefanos N KalesDivision of Sleep Medicine, Harvard Medical School, Boston, MA.
University of Minnesota Morris · USHarvard University · USVirginia Tech · USPrecision Therapeutics (United States) · USUniversity of California, San Diego · US

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
Single Motor Unit Genioglossus Recordings to Understand Sleep Apnea PathogenesisR01HL085188 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2008 to 2018
$3.5M
Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
Assessment of Upper Airway Mechanics Using Newer Electromyographic TechniquesK24HL132105 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2016 to 2020
$611k
NCRR NIH HHS UL1 RR025758NHLBI NIH HHS K24 HL132105NHLBI NIH HHS R01 HL085188NHLBI NIH HHS T32 HL134632
6 · The paper itself

Abstract

STUDY

objectivesTo evaluate the effect of an employer-mandated obstructive sleep apnea (OSA) program on the risk of serious preventable truck crashes.

methodsData are from the first large-scale, employer-mandated program to screen, diagnose, and monitor OSA treatment adherence in the US trucking industry. A retrospective analysis of cohorts was constructed: polysomnogram-diagnosed drivers (OSA positive n = 1,613, OSA negative n = 403) were matched to control drivers unlikely to have OSA (n = 2,016) on two factors affecting crash risk, experience-at-hire and length of job tenure; tenure was matched on the date of each diagnosed driver's polysomnogram. Auto-adjusting positive airway pressure (APAP) treatment was provided to all cases (i.e. OSA positive drivers); treatment adherence was objectively monitored. Cases were grouped by treatment adherence: "Full Adherence" (n = 682), "Partial Adherence" (n = 571), or "No Adherence" (n = 360). Preventable Department-of-Transportation-reportable crashes/100,000 miles were compared across study subgroups. Robustness was assessed.

resultsAfter the matching date, "No Adherence" cases had a preventable Department of Transportation-reportable crash rate that was fivefold greater (incidence rate ratio = 4.97, 95% confidence interval: 2.09, 10.63) than that of matched controls (0.070 versus 0.014 per 100,000 miles). The crash rate of "Full Adherence" cases was statistically similar to controls (incidence rate ratio = 1.02, 95% confidence interval: 0.48, 2.04; 0.014 per 100,000 miles).

conclusionsNontreatment-adherent OSA-positive drivers had a fivefold greater risk of serious preventable crashes, but were discharged or quit rapidly, being retained only one-third as long as other subjects. Thus, the mandated program removed risky nontreatment-adherent drivers and retained adherent drivers at the study firm. Current regulations allow nonadherent OSA cases to drive at another firm by keeping their diagnosis private. COMMENTARY: A commentary on this article appears in this issue on page 961.

Indexed as

Automobile DrivingMandatory ProgramsMotor VehiclesOccupational Health ServicesAccidents, TrafficAdultFemaleHumansMaleMass ScreeningMiddle AgedPatient CompliancePolysomnographyRetrospective StudiesRisk FactorsSleep Apnea, ObstructiveAPAPcommercial motor vehicle operatorCPAPmotor carrierobstructive sleep apneaOSApreventable crashPSGscreeningtruckload

Identifiers

PMID27070139
PMCPMC4835318
OpenAlexW2344362748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.