Evidence map›Paper›PMID 27069873›Full record

ReviewPhotoacoustics2016

Bond-selective photoacoustic imaging by converting molecular vibration into acoustic waves.

Jie Hui, Rui Li, Evan H Phillips, Craig J Goergen, Michael Sturek, Ji-Xin Cheng

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Photoacoustics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. New "HOPE" laser for photoacoustic imaging of water.Light, science & applications · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie HuiDepartment of Physics and Astronomy, Purdue University, West Lafayette, IN 47907, USA.
Rui LiWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Evan H PhillipsWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Craig J GoergenWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Michael SturekWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Ji-Xin ChengWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA; Purdue Institute of Inflammation, Immunology and Infectious Diseases, West Lafayette, IN 47907, USA.

Funding

Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Sensing Vulnerable Plaque in vivo by an All-optical Intravascular Ultrasound and Photoacoustic CatheterR01HL125385 · NHLBI · PURDUE UNIVERSITY · PI CHENG, JI-XIN · 2015 to 2023
$4.6M
NHLBI NIH HHS R01 HL125385NIDDK NIH HHS P30 DK097512
6 · The paper itself

Abstract

The quantized vibration of chemical bonds provides a way of detecting specific molecules in a complex tissue environment. Unlike pure optical methods, for which imaging depth is limited to a few hundred micrometers by significant optical scattering, photoacoustic detection of vibrational absorption breaks through the optical diffusion limit by taking advantage of diffused photons and weak acoustic scattering. Key features of this method include both high scalability of imaging depth from a few millimeters to a few centimeters and chemical bond selectivity as a novel contrast mechanism for photoacoustic imaging. Its biomedical applications spans detection of white matter loss and regeneration, assessment of breast tumor margins, and diagnosis of vulnerable atherosclerotic plaques. This review provides an overview of the recent advances made in vibration-based photoacoustic imaging and various biomedical applications enabled by this new technology.

Indexed as

AtherosclerosisIntravascular photoacousticLipidOvertone absorptionPhotoacoustic microscopyPhotoacoustic tomographyTumor margin

Identifiers

PMID27069873
PMCPMC4811918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.