ArticleThe Cochrane database of systematic reviews2016
Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews.
Article in The Cochrane database of systematic reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Interventions for chronic kidney disease in people with sickle cell disease.The Cochrane database of systematic reviews · 2023Pooled it
- Article
- Commonly used agent for acute pain management of sickle cell anemia in Saudi Emergency Department: A narrative review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021Review
- Hemoglobin S monitoring on TOSOH G8 in hemoglobin A1c mode in case of urgent red blood cell exchange.Journal of clinical laboratory analysis · 2018Article
- An introduction to overviews of reviews: planning a relevant research question and objective for an overview.Systematic reviews · 2018Article
- Engineering the Surface of Therapeutic "Living" Cells.Chemical reviews · 2018Review
- Simple chronic transfusion therapy, a crucial therapeutic option for sickle cell disease, improves but does not normalize blood rheology: What should be our goals for transfusion therapy?Clinical hemorheology and microcirculation · 2018Article
- Selecting and implementing overview methods: implications from five exemplar overviews.Systematic reviews · 2017Review
- Knowledge insufficient: the management of haemoglobin SC disease.British journal of haematology · 2017Review
Corrections and comments
- Updated by
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
This is the protocol for a review and there is no abstract. The objectives are as follows: To summarize the evidence in Cochrane reviews of the effectiveness and safety of red cell transfusions versus no transfusion, or restrictive (to increase the total haemoglobin) versus liberal (to decrease the haemoglobin S level below a specified percentage) transfusion, for treatment or prevention of complications experienced by people with SCD.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.