ReviewDialogues in clinical neuroscience2016
Striatal dopamine, reward, and decision making in schizophrenia.
Review in Dialogues in clinical neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Brexpiprazole vs. Aripiprazole in Patients with Schizophrenia with or Without Comorbid Substance Use Disorder: A 12-Month Real-World Naturalistic Study of Efficacy.Brain sciences · 2026Article
- Association of the endosomal sorting processes cargo selection and membrane tubulation with human reward system reactivity.European archives of psychiatry and clinical neuroscience · 2026Article
- The indirect pathway hypothesis of schizophrenia: insights from perinatal asphyxia.Frontiers in physiology · 2026Review
- Blood‑brain barrier dysfunction in schizophrenia: Mechanisms and implications (Review).International journal of molecular medicine · 2025Review
- Modeling Decision-Making in Schizophrenia: Associations Between Computationally Derived Risk Propensity and Self-Reported Risk Perception.Schizophrenia bulletin · 2024Article
- Diminished differentiation of rewards in individuals at clinical high-risk for psychosis.European archives of psychiatry and clinical neuroscience · 2024Article
- Linking haploinsufficiency of the autism- and schizophrenia-associated gene Cyfip1 with striatal-limbic-cortical network dysfunction and cognitive inflexibility.Translational psychiatry · 2024Article
- Dopamine, Psychosis, and Symptom Fluctuation: A Narrative Review.Healthcare (Basel, Switzerland) · 2022Review
- Analysis of individual differences in neurofeedback training illuminates successful self-regulation of the dopaminergic midbrain.Communications biology · 2022Article
- A review of risky decision-making in psychosis-spectrum disorders.Clinical psychology review · 2022Review
- Computational reinforcement learning, reward (and punishment), and dopamine in psychiatric disorders.Frontiers in psychiatry · 2022Review
- Investigating the Relationship between White Matter Connectivity and Motivational Circuits in Subjects with Deficit Schizophrenia: A Diffusion Tensor Imaging (DTI) Study.Journal of clinical medicine · 2021Article
- Neurochemistry of Visual Attention.Frontiers in neuroscience · 2021Review
- Differences in Functional Connectivity Networks Related to the Midbrain Dopaminergic System-Related Area in Various Psychiatric Disorders.Schizophrenia bulletin · 2020Article
- Reward, Control & Decision-Making in Cannabis Use Disorder: Insights from Functional MRI.The British journal of radiology · 2019Review
- Differential neural reward mechanisms in treatment-responsive and treatment-resistant schizophrenia.Psychological medicine · 2018Article
- Dopamine D2 -141C Ins/Del and Taq1A polymorphisms, body mass index, and prediction error brain response.Translational psychiatry · 2018Article
- Functional dysconnectivity of the limbic loop of frontostriatal circuits in first-episode, treatment-naive schizophrenia.Human brain mapping · 2018Article
- fMRI correlates of jumping-to-conclusions in patients with delusions: Connectivity patterns and effects of metacognitive training.NeuroImage. Clinical · 2018Observational
- Free Energy and Virtual Reality in Neuroscience and Psychoanalysis: A Complexity Theory of Dreaming and Mental Disorder.Frontiers in psychology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elevated striatal dopamine function is one of the best-established findings in schizophrenia. In this review, we discuss causes and consequences of this striata! dopamine alteration. We first summarize earlier findings regarding striatal reward processing and anticipation using functional neuroimaging. Secondly, we present a series of recent studies that are exemplary for a particular research approach: a combination of theory-driven reinforcement learning and decision-making tasks in combination with computational modeling and functional neuroimaging. We discuss why this approach represents a promising tool to understand underlying mechanisms of symptom dimensions by dissecting the contribution of multiple behavioral control systems working in parallel. We also discuss how it can advance our understanding of the neurobiological implementation of such functions. Thirdly, we review evidence regarding the topography of dopamine dysfunction within the striatum. Finally, we present conclusions and outline important aspects to be considered in future studies.
Indexed as
Identifiers
27069382PMC4826774What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.