Evidence map›Paper›PMID 27068957›Full record

ReviewBiochemical Society transactions2016

Cell surface recycling in yeast: mechanisms and machineries.

Chris MacDonald, Robert C Piper

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Rethinking the Yeast Endomembrane System.Sub-cellular biochemistry · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Life and Death of Fungal Transporters under the Challenge of Polarity.International journal of molecular sciences · 2020
    Review
  8. Article
  9. Article
  10. Endosomal trafficking of yeast membrane proteins.Biochemical Society transactions · 2018
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chris MacDonaldMolecular Physiology and Biophysics, University of Iowa, Iowa City, IA 52242, U.S.A. chris-macdonald@uiowa.edu.
Robert C PiperMolecular Physiology and Biophysics, University of Iowa, Iowa City, IA 52242, U.S.A.
University of Iowa · US

Funding

Ubiquitin-Dependent Sorting in Endosomes and the TGNR01GM058202 · NIGMS · UNIVERSITY OF IOWA · PI PIPER, ROBERT C · 1998 to 2025
$8.9M
NIGMS NIH HHS R01 GM058202NIGMS NIH HHS R01-GM058202
6 · The paper itself

Abstract

Sorting internalized proteins and lipids back to the cell surface controls the supply of molecules throughout the cell and regulates integral membrane protein activity at the surface. One central process in mammalian cells is the transit of cargo from endosomes back to the plasma membrane (PM) directly, along a route that bypasses retrograde movement to the Golgi. Despite recognition of this pathway for decades we are only beginning to understand the machinery controlling this overall process. The budding yeastSaccharomyces cerevisiae, a stalwart genetic system, has been routinely used to identify fundamental proteins and their modes of action in conserved trafficking pathways. However, the study of cell surface recycling from endosomes in yeast is hampered by difficulties that obscure visualization of the pathway. Here we briefly discuss how recycling is likely a more prevalent process in yeast than is widely appreciated and how tools might be built to better study the pathway.

Indexed as

Cell MembraneEndocytosisOrganellesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsUbiquitinationSaccharomyces cerevisiae Proteinscell surface recyclingdeubiquitinationendocytosisyeast

Identifiers

PMID27068957
PMCPMC5019169
OpenAlexW2316890051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.