Evidence map›Paper›PMID 27068929›Full record

ArticleAnnals of intensive care2016

Outcome of a cohort of severe cerebral venous thrombosis in intensive care.

Benjamin Soyer, Marco Rusca, Anne-Claire Lukaszewicz, Isabelle Crassard, Jean-Pierre Guichard, Damien Bresson, Joaquim Mateo, Didier Payen

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Annals of intensive care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  6. Article
  7. Review
  8. Cerebral Venous Thrombosis: an Update.Current neurology and neuroscience reports · 2019
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Cerebral venous thrombosis.Nature reviews. Neurology · 2017
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Benjamin SoyerDepartment of Anesthesiology and Critical Care and SMUR, Hôpital Lariboisière, AP-HP, 2 Rue Ambroise Paré, 75010, Paris, France.
Marco RuscaDepartment of Anesthesiology and Critical Care and SMUR, Hôpital Lariboisière, AP-HP, 2 Rue Ambroise Paré, 75010, Paris, France.
Anne-Claire LukaszewiczDepartment of Anesthesiology and Critical Care and SMUR, Hôpital Lariboisière, AP-HP, 2 Rue Ambroise Paré, 75010, Paris, France.
Isabelle CrassardDépartement Hospitalo-Universitaire (DHU) Neuro-Vasculaire, P R E S Paris Sorbonne Cité, Paris, France.
Jean-Pierre GuichardDépartement Hospitalo-Universitaire (DHU) Neuro-Vasculaire, P R E S Paris Sorbonne Cité, Paris, France.
Damien BressonDépartement Hospitalo-Universitaire (DHU) Neuro-Vasculaire, P R E S Paris Sorbonne Cité, Paris, France.
Joaquim MateoDepartment of Anesthesiology and Critical Care and SMUR, Hôpital Lariboisière, AP-HP, 2 Rue Ambroise Paré, 75010, Paris, France.
Didier PayenDepartment of Anesthesiology and Critical Care and SMUR, Hôpital Lariboisière, AP-HP, 2 Rue Ambroise Paré, 75010, Paris, France. dpayen1234@orange.fr.
Assistance Publique – Hôpitaux de Paris · FRDélégation Paris 7 · FRHôpital Lariboisière · FRSorbonne Paris Cité · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeverity of cerebral venous thrombosis (CVT) may require the transfer to intensive care unit (ICU). This report described the context for CVT transfer to ICU, the strategy of care and the outcome after 1 year.

methodsMonocentric cohort of 41 consecutive CVT admitted in a French ICU tertiary hospital (National Referent Center for CVT). Data collected are as follows: demographic data, clinical course, incidence of craniectomy and/or endovascular procedures and outcome in ICU, after 3 and 12 months.

results47 years old (IQ 26-53), with 73.2 % were female, having a SAPS II 41 (32-45), GCS 7 (5-8), and at least one episode of mydriasis in 48.8 %. Thrombosis location was 80.5 % in lateral sinus and 53.7 % in superior sagittal sinus; intracranial hematoma was present in 78.0 %, signs of intracranial hypertension in 60.9 %, cerebral edema in 58.5 % and venous ischemia in 43.9 %. All patients received heparin therapy, and 9 cases had endovascular treatment (21.9 %); osmotherapy (53.7 %) and decompressive craniectomy (16 cases, 39 %) necessary to control intracranial hypertension. Ten patients/41 (24.4 %) died in ICU and 18/31 (58.1 %) were discharged from ICU with outcome 0-3 of mRS. After 12 months, 92 % of survivors (23/25) had a mRS between 0 and 3. The proportion of death was 31.7 % at 1 year.

conclusionsThe large proportion of acceptable outcome in survivors, which continue to functionally improve after 1 year, motivates the hospitalization in ICU for severe CVT. For similar CVT severity, craniectomy did not improve outcome in comparison with the absence of craniectomy.

Indexed as

Decompressive craniectomyEndovascular therapiesIntracranial hematomaIntracranial hypertensionMultimodal monitoringNeuro-resuscitationSevere cerebral venous thrombosis

Identifiers

PMID27068929
PMCPMC4828343
OpenAlexW2338532825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.