Evidence map›Paper›PMID 27068829›Full record

ArticleJournal of nephrology2017

The modified CKD-EPI equation may be not more accurate than CKD-EPI equation in determining glomerular filtration rate in Chinese patients with chronic kidney disease.

Peng Xie, Jian-Min Huang, Ying Li, Huai-Jun Liu, Yan Qu

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in Journal of nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Neuropad Assessment of Sudomotor Function Across Glycemic Levels in Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Article
  2. Article
  3. Article
  4. Estimated GFR: time for a critical appraisal.Nature reviews. Nephrology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peng XieInstitute of Nuclear Medicine, The Third Hospital, Hebei Medical University, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei, 050051, People's Republic of China.
Jian-Min HuangInstitute of Nuclear Medicine, The Third Hospital, Hebei Medical University, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei, 050051, People's Republic of China.
Ying LiInstitute of Nephrology, The Third Hospital, Hebei Medical University, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei, 050051, People's Republic of China.
Huai-Jun LiuInstitute of Radiology, the Second Hospital, Hebei Medical University, No.215 Heping Road, Xinhua District, Shijiazhuang, Hebei, 050005, People's Republic of China. woxinfly1982@126.com.
Yan QuDepartment of Research, The Third Hospital, Hebei Medical University, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, Hebei, 050051, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the application of the new modified Chronic Kidney Disease Epidemiology Collaboration (mCKD-EPI) equation developed by Liu for the measurement of glomerular filtration rate (GFR) in Chinese patients with chronic kidney disease (CKD) and to evaluate whether this modified form is more accurate than the original one in clinical practice.

methodsGFR was determined simultaneously by 3 methods: (a)

resultsA total of 170 patients were enrolled. Both eGFRckdepi and eGFRmodified correlated well with mGFR (concordance correlation coefficient 0.90 and 0.74, respectively) and the Passing-Bablok regression equation of eGFRckdepi and eGFRmodified against mGFR was mGFR = 0.37 + 1.04 eGFRckdepi and -49.25 + 1.74 eGFRmodified, respectively. In terms of bias, precision and 30 % accuracy, eGFRmodified showed a worse performance compared to eGFRckdepi, in the whole cohort.

conclusionsThe new modified CKD-EPI equation cannot replace the original CKD-EPI equation in determining GFR in Chinese patients with CKD.

Indexed as

Glomerular Filtration RateModels, BiologicalAdultAgedAsian PeopleBiomarkersChinaCreatinineFemaleHumansKidneyMaleMiddle AgedPredictive Value of TestsRadiopharmaceuticalsRenal Insufficiency, ChronicBiomarkersCreatinineRadiopharmaceuticalsTechnetium Tc 99m PentetateChronic kidney diseaseCKD-EPI equationGlomerular filtration rateModified CKD-EPI equation

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.