Evidence map›Paper›PMID 27068437›Full record

ReviewCurrent hematologic malignancy reports2016

Which Patients With Mantle Cell Lymphoma Do Not Need Aggressive Therapy.

Jia Ruan, Peter Martin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hematologic malignancy reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jia RuanDivision of Hematology and Medical Oncology, Meyer Cancer Center, Weill Cornell Medical College, 1305 York Avenue, New York, NY, 10065, USA. jruan@med.cornell.edu.
Peter MartinDivision of Hematology and Medical Oncology, Meyer Cancer Center, Weill Cornell Medical College, 1305 York Avenue, New York, NY, 10065, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mantle cell lymphoma (MCL) is a heterogeneous disease, and it has been well-established over the last decade that a subset of patients can have indolent presentation. It is therefore important to adopt a risk-stratified approach in order to minimize unnecessary toxicities while maximizing survival and quality of life in selected MCL patients. This review provides an up-to-date assessment of clinical and pathologic entities associated with indolent disease course and delineates available biomarkers with predictive significance. Initial treatment decisions should be guided by risk assessment to discern patients who might do well with deferred therapy, from those who would require treatment with non-aggressive first-line regimens.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorHumansImmunoglobulin Heavy ChainsKi-67 AntigenLymphoma, Mantle-CellSOXC Transcription FactorsTumor Suppressor Protein p53Biomarkers, TumorImmunoglobulin Heavy ChainsKi-67 AntigenSOXC Transcription FactorsTumor Suppressor Protein p53BiomarkersHematologyMantle cell lymphomaTreatment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.