ArticleEnvironmental health : a global access science source2016
Maternal levels of endocrine disruptors, polybrominated diphenyl ethers, in early pregnancy are not associated with lower birth weight in the Canadian birth cohort GESTE.
Article in Environmental health : a global access science source, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Association between maternal exposure to mercury during pregnancy and birth weight: a systematic review and meta-analysis.BMC pediatrics · 2026Pooled it
- The relationship between persistent organic pollutants and Attention Deficit Hyperactivity Disorder phenotypes: Evidence from task-based neural activity in an observational study of a community sample of Canadian mother-child dyads.Environmental research · 2022Pooled it
- Correlation between Prenatal Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Infant Birth Outcomes: A Meta-Analysis and an Experimental Study.International journal of environmental research and public health · 2017Pooled it
- Halogenated flame retardant exposure was associated with pediatric gut microbiome profiles in a Canadian cohort.Gut microbes reports · 2026Article
- Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food.EFSA journal. European Food Safety Authority · 2024Article
- Review
- Endocrine Disrupting Chemicals' Effects in Children: What We Know and What We Need to Learn?International journal of molecular sciences · 2022Review
- Associations Between Polybrominated Diphenyl Ethers Concentrations in Human Placenta and Small for Gestational Age in Southwest China.Frontiers in public health · 2022Article
- Associations of Childhood and Perinatal Blood Metals with Children's Gut Microbiomes in a Canadian Gestation Cohort.Environmental health perspectives · 2022Article
- Article
- Exploring associations between prenatal exposure to multiple endocrine disruptors and birth weight with exposure continuum mapping.Environmental research · 2021Article
- The association between prenatal concentrations of polybrominated diphenyl ether and child cognitive and psychomotor function.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
- Association of Prenatal Acetaminophen Exposure Measured in Meconium With Risk of Attention-Deficit/Hyperactivity Disorder Mediated by Frontoparietal Network Brain Connectivity.JAMA pediatrics · 2020Observational
- Endocrine-Disrupting Chemicals in Human Fetal Growth.International journal of molecular sciences · 2020Review
- Exposure to Persistent Organic Pollutants and Birth Characteristics: The Upstate KIDS Study.Epidemiology (Cambridge, Mass.) · 2019Article
- Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting.International journal of molecular sciences · 2018Review
- Gestational exposure to endocrine disrupting chemicals in relation to infant birth weight: a Bayesian analysis of the HOME Study.Environmental health : a global access science source · 2017Article
- Early-life chemical exposures and risk of metabolic syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2017Review
- Environmental influences on reproductive health: the importance of chemical exposures.Fertility and sterility · 2016Review
- Complex systems dynamics in aging: new evidence, continuing questions.Biogerontology · 2016Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPolybrominated diphenyl ethers are known endocrine disrupting environmental contaminants used as flame retardants. Their levels have increased in humans over the last ten years, raising concerns about their consequences on human health. Some animal studies suggest that PBDEs can affect fetal growth; however, the results of human studies are contradictory. This study evaluates the association between the most common PBDEs in maternal blood measured in early pregnancy and birth weight.
methodsBDE-47, BDE-99, BDE-100 and BDE-153 levels were measured in 349 women during their first prenatal care visit at the University Hospital Center of Sherbrooke (Quebec, Canada). Birth weight and relevant medical information were collected from medical records. In contrast with previous studies, we examined the full range of clinical risk factors known to affect fetal growth as potential confounders, as well as other environmental pollutants that are likely to interact with fetal growth (polychlorinated biphenyls (PCBs), mercury, lead, cadmium and manganese).
resultsThere was no statistically significant relationship between PBDE levels in early pregnancy and birth weight in both unadjusted and multivariate regression models.
conclusionsOur results suggest that PBDEs in early pregnancy have little or no direct impact on birth weight, at least at the levels of exposure in our population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.