ArticleScientific reports2016
Molar concentration from sequential 2-D water-window X-ray ptychography and X-ray fluorescence in hydrated cells.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- X-ray-Based Techniques to Study the Nano-Bio Interface.ACS nano · 2021Article
- Simultaneous structural and elemental nano-imaging of human brain tissue.Chemical science · 2020Article
- Multimodal x-ray and electron microscopy of the Allende meteorite.Science advances · 2019Article
- Resolving 500 nm axial separation by multi-slice X-ray ptychography.Acta crystallographica. Section A, Foundations and advances · 2019Article
- High Reflectance Nanoscale V/Sc Multilayer for Soft X-ray Water Window Region.Scientific reports · 2017Article
- Correlative cellular ptychography with functionalized nanoparticles at the Fe L-edge.Scientific reports · 2017Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent developments in biological X-ray microscopy have allowed structural information and elemental distribution to be simultaneously obtained by combining X-ray ptychography and X-ray fluorescence microscopy. Experimentally, these methods can be performed simultaneously; however, the optimal conditions for each measurement may not be compatible. Here, we combine two distinct measurements of ultrastructure and elemental distribution, with each measurement performed under optimised conditions. By combining optimised ptychography and fluorescence information we are able to determine molar concentrations from two-dimensional images, allowing an investigation into the interactions between the environment sensing filopodia in fibroblasts and extracellular calcium. Furthermore, the biological ptychography results we present illustrate a point of maturity where the technique can be applied to solve significant problems in structural biology.
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