Evidence map›Paper›PMID 27067530›Full record

ReviewNature reviews. Nephrology2016

Radiologic imaging of the renal parenchyma structure and function.

Nicolas Grenier, Pierre Merville, Christian Combe

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
19.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03716401 recruitingnot on this mapstarted 2018, after this paper: background citation

Prognostic Imaging Biomarkers for Diabetic Kidney Disease

TypeobservationalSponsorUniversity of LeedsRan2018 to 2038Enrolled500ConditionsDiabetic Kidney DiseaseArmsMRI (magnetic resonance imaging), US (ultrasound), Renal Biopsy, Positron Emission Tomography (PET), Microvascular Assessment
NCT06884410 narecruitingnot on this mapstarted 2025, after this paper: background citation

Reproducibility of Multiparametric Renal Magnetic Resonance Imaging on 1.5T MRI Scanners (RESPECT_1.5T Sub-study)

TypeinterventionalSponsorMario Negri Institute for Pharmacological ResearchRan2025 to 2026Enrolled48ConditionsMultiparametric MRIArmsMRI
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 83 citations in OpenAlex.

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  6. Review
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  9. MRI of kidney size matters.Magma (New York, N.Y.) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicolas GrenierService d'Imagerie Diagnostique et Interventionnelle de l'Adulte, Centre Hospitalier Universitaire de Bordeaux, Groupe Hospitalier Pellegrin, Place Amélie Raba-Léon, 33076 Bordeaux Cedex, France.
Pierre MervilleUniversity of Bordeaux, Rue Léo Saignat, 33076 Bordeaux Cedex, France.
Christian CombeService de Néphrologie Transplantation Dialyse, Centre Hospitalier Universitaire de Bordeaux, Groupe Hospitalier Pellegrin, Place Amélie Raba-Léon, 33076 Bordeaux Cedex, France.
Centre Hospitalier Universitaire de Bordeaux · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiologic imaging has the potential to identify several functional and/or structural biomarkers of acute and chronic kidney diseases that are useful diagnostics to guide patient management. A renal ultrasound examination can provide information regarding the gross anatomy and macrostructure of the renal parenchyma, and ultrasound imaging modalities based on Doppler or elastography techniques can provide haemodynamic and structural information, respectively. CT is also able to combine morphological and functional information, but the use of CT is limited due to the required exposure to X-ray irradiation and a risk of contrast-induced nephropathy following intravenous injection of a radio-contrast agent. MRI can be used to identify a wide range of anatomical and physiological parameters at the tissue and even cellular level, such as tissue perfusion, oxygenation, water diffusion, cellular phagocytic activity, tissue stiffness, and level of renal filtration. The ability of MRI to provide valuable information for most of these parameters within a renal context is still in development and requires more clinical experience, harmonization of technical procedures, and an evaluation of reliability and validity on a large scale.

Indexed as

AnimalsHumansKidneyKidney DiseasesMagnetic Resonance ImagingOxygenParenchymal TissueTomography, X-Ray ComputedUltrasonographyOxygen

Identifiers

PMID27067530
OpenAlexW2336189760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.