Evidence map›Paper›PMID 27067408›Full record

ReviewFuture oncology (London, England)2016

Metabolic syndrome in prostate cancer: impact on risk and outcomes.

Fatima H Karzai, Ravi A Madan, William L Dahut

Open access · bronzeAbstract readReview
In one paragraph

Review in Future oncology (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fatima H KarzaiGenitourinary Malignancies Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Ravi A MadanGenitourinary Malignancies Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
William L DahutGenitourinary Malignancies Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
National Cancer Institute · US

Funding

The Evaluation of Novel Therapeutics for Genitourinary MalignanciesZIASC010098 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI DAHUT, WILLIAM L. · 2009 to 2022
$7.6M
6 · The paper itself

Abstract

Androgen-deprivation therapy (ADT) is a fundamental element of treatment for nonlocalized prostate cancer and for patients with high-risk disease who are not candidates for radical treatment. ADT has been linked to metabolic syndrome, which involves changes in metabolic factors. While distinct from classic metabolic syndrome, this type does include changes in body composition, lipid profiles and insulin resistance. The constellation of risk factors may be associated with cardiovascular morbidity and the onset of diabetes mellitus. Physicians should discuss in detail the risk and benefits of ADT, as well as any needed lifestyle modifications with patients before beginning therapy.

Indexed as

Androgen AntagonistsHumansMaleMetabolic SyndromeProstatic NeoplasmsAndrogen Antagonistsandrogen-deprivation therapyandrogen receptorcardiovascular riskdiabetesgonadotropin-releasing hormone agonist/antagonisthypertriglyceridemiainsulin resistancemetabolic syndromeprostate cancer

Identifiers

PMID27067408
PMCPMC5551937
OpenAlexW2340422542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.