Evidence map›Paper›PMID 27067208›Full record

ArticleJournal of fluorescence2016

DNA Binding Behavior, Sensor Studies, Antimicrobial, Photocleavage and In vitro Cytotoxicity of Synthesized Ru(II) Complexes with Assorted Intercalating Polypyridyl Ligands.

Rajender Reddy Mallepally, Venkat Reddy Putta, Nagamani Chintakuntla, Ravi Kumar Vuradi, Laxma Reddy Kotha, Satyanarayana Sirasani

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rajender Reddy MallepallyDepartment of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana State, 500007, India.
Venkat Reddy PuttaDepartment of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana State, 500007, India.
Nagamani ChintakuntlaDepartment of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana State, 500007, India.
Ravi Kumar VuradiDepartment of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana State, 500007, India.
Laxma Reddy KothaDepartment of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana State, 500007, India.
Satyanarayana SirasaniDepartment of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana State, 500007, India. ssnsirasani@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The four novel Ru(II) polypyridyl complexes of [Ru(Hdpa)2dmbip](2+) (1), [Ru(Hdpa)2NO2-dmbip](2+) (2), [Ru(Hdpa)2debip](2+) (3) and [Ru(Hdpa)2OH-debip](2+) (4) where Hdpa = 2,2'-bipyridylamine, dmbip = 2-(4-N,N-dimethylbenzenamine)1H-imidazo[4,5-f][1,10]phenanthroline, debip = 2-(4-N,N-diethylbenzenamine)1H-imidazo[4,5-f][1,10]phenanthroline, NO2-dmbip = NO2-2-(4-N,N-dimethylbenzenamine)1H-imidazo[4,5-f][1,10]phenanthroline, OH-debip = OH-2-(4-N,N-diethylbenzenamine)1H-imidazo[4,5-f][1,10]phenanthroline were synthesized and fully characterized using elemental analysis, Mass, NMR and FT-IR. The DNA binding behavior of all synthesized complexes were investigated by using electronic absorption spectra, emission spectra, cyclic light switch on and off, sensor studies, electrochemical method and viscosity titrations. Docking studies were performed with human DNA TOP1 by using LibDock. Furthermore explore antimicrobial activity, photocleavage and in vitro cytotoxicity assay of four Ru(II) complexes.

Indexed as

Photochemical ProcessesAnti-Bacterial AgentsChemistry Techniques, SyntheticCoordination ComplexesDNADNA CleavageDNA Topoisomerases, Type IEscherichia coliHeLa CellsHumansIntercalating AgentsLigandsMolecular Docking SimulationPhenanthrolinesProtein ConformationPyridinesAnti-Bacterial AgentsCoordination ComplexesDNADNA Topoisomerases, Type IIntercalating AgentsLigandsPhenanthrolinespyridinePyridinesRutheniumAntimicrobial activityDNA bindingIn vitro cytotoxicityPhotocleavageRu(II) polypyridyl complexes

Identifiers

PMID27067208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.