ArticleScientific reports2016
Neurons in the inferior colliculus of the rat show stimulus-specific adaptation for frequency, but not for intensity.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 54 citations in OpenAlex.
- Stimulus statistical context sensitivity of deviant responses to auditory intensity changes.Scientific reports · 2026Article
- Sex- and etiology-specific effects on predictive processing in the inferior colliculus of two rat models of autism.Communications biology · 2026Article
- Contextual auditory processing in the inferior colliculus is affected in a sex- and age-dependent manner in the valproic acid-induced rat model of autism.PLoS biology · 2025Article
- Hierarchical Temporal Processing in the Primate Thalamocortical System: Insights from Nonlinguistic Structured Stimuli.Research (Washington, D.C.) · 2025Article
- Two Prediction Error Systems in the Nonlemniscal Inferior Colliculus: "Spectral" and "Nonspectral".The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Fast frequency modulation is encoded according to the listener expectations in the human subcortical auditory pathway.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- The influence of phoneme contexts on adaptation in vowel-evoked envelope following responses.The European journal of neuroscience · 2022Article
- Alzheimer's Disease, Hearing Loss, and Deviance Detection.Frontiers in neuroscience · 2022Article
- Adjudicating Between Local and Global Architectures of Predictive Processing in the Subcortical Auditory Pathway.Frontiers in neural circuits · 2021Review
- Cortical mapping of mismatch responses to independent acoustic features.Hearing research · 2021Article
- Neural Responses and Perceptual Sensitivity to Sound Depend on Sound-Level Statistics.Scientific reports · 2020Article
- Neural circuits underlying auditory contrast gain control and their perceptual implications.Nature communications · 2020Article
- Cortical Microcircuit Mechanisms of Mismatch Negativity and Its Underlying Subcomponents.Frontiers in neural circuits · 2020Review
- Neurons along the auditory pathway exhibit a hierarchical organization of prediction error.Nature communications · 2017Article
- Endocannabinoid Modulation of Stimulus-Specific Adaptation in Inferior Colliculus Neurons of the Rat.Scientific reports · 2017Article
- Spatial Processing Is Frequency Specific in Auditory Cortex But Not in the Midbrain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Stimulus-specific adaptation to visual but not auditory motion direction in the barn owl's optic tectum.The European journal of neuroscience · 2017Article
- Review
- The Neuronal Basis of Predictive Coding Along the Auditory Pathway: From the Subcortical Roots to Cortical Deviance Detection.Trends in hearingReview
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
Electrophysiological and psychophysical responses to a low-intensity probe sound tend to be suppressed by a preceding high-intensity adaptor sound. Nevertheless, rare low-intensity deviant sounds presented among frequent high-intensity standard sounds in an intensity oddball paradigm can elicit an electroencephalographic mismatch negativity (MMN) response. This has been taken to suggest that the MMN is a correlate of true change or "deviance" detection. A key question is where in the ascending auditory pathway true deviance sensitivity first emerges. Here, we addressed this question by measuring low-intensity deviant responses from single units in the inferior colliculus (IC) of anesthetized rats. If the IC exhibits true deviance sensitivity to intensity, IC neurons should show enhanced responses to low-intensity deviant sounds presented among high-intensity standards. Contrary to this prediction, deviant responses were only enhanced when the standards and deviants differed in frequency. The results could be explained with a model assuming that IC neurons integrate over multiple frequency-tuned channels and that adaptation occurs within each channel independently. We used an adaptation paradigm with multiple repeated adaptors to measure the tuning widths of these adaption channels in relation to the neurons' overall tuning widths.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.