Evidence map›Paper›PMID 27066433›Full record

ArticleThe Korean journal of thoracic and cardiovascular surgery2016

Role of Barium Swallow in Diagnosing Clinically Significant Anastomotic Leak following Esophagectomy.

Simon Roh, Mark D Iannettoni, John C Keech, Mohammad Bashir, Peter J Gruber, Kalpaj R Parekh

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of thoracic and cardiovascular surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Simon RohDepartment of Radiology, University of Iowa Hospitals and Clinics.
Mark D IannettoniDepartment of Cardiovascular Sciences, Brody School of Medicine, East Carolina University.
John C KeechDepartment of Cardiothoracic Surgery, University of Iowa Hospitals and Clinics.
Mohammad BashirDepartment of Cardiothoracic Surgery, University of Iowa Hospitals and Clinics.
Peter J GruberDepartment of Cardiothoracic Surgery, University of Iowa Hospitals and Clinics.
Kalpaj R ParekhDepartment of Cardiothoracic Surgery, University of Iowa Hospitals and Clinics.
University of Iowa Hospitals and Clinics · USEast Carolina University · US

Funding

Epithelial Stem Cells in Lung TransplantationK08HL114725 · NHLBI · UNIVERSITY OF IOWA · PI PAREKH, KALPAJ RAJNIKANT · 2012 to 2015
$511k
NHLBI NIH HHS K08 HL114725
6 · The paper itself

Abstract

backgroundBarium swallow is performed following esophagectomy to evaluate the anastomosis for detection of leaks and to assess the emptying of the gastric conduit. The aim of this study was to evaluate the reliability of the barium swallow study in diagnosing anastomotic leaks following esophagectomy.

methodsPatients who underwent esophagectomy from January 2000 to December 2013 at our institution were investigated. Barium swallow was routinely done between days 5-7 to detect a leak. These results were compared to clinically determined leaks (defined by neck wound infection requiring jejunal feeds and or parenteral nutrition) during the postoperative period. The sensitivity and specificity of barium swallow in diagnosing clinically significant anastomotic leaks was determined.

resultsA total of 395 esophagectomies were performed (mean age, 62.2 years). The indications for the esophagectomy were as follows: malignancy (n=320), high-grade dysplasia (n=14), perforation (n=27), benign stricture (n=7), achalasia (n=16), and other (n=11). A variety of techniques were used including transhiatal (n=351), McKeown (n=35), and Ivor Lewis (n=9) esophagectomies. Operative mortality was 2.8% (n=11). Three hundred and sixty-eight patients (93%) underwent barium swallow study after esophagectomy. Clinically significant anastomotic leak was identified in 36 patients (9.8%). Barium swallow was able to detect only 13/36 clinically significant leaks. The sensitivity of the swallow in diagnosing a leak was 36% and specificity was 97%. The positive and negative predictive values of barium swallow study in detecting leaks were 59% and 93%, respectively.

conclusionBarium swallow is an insensitive but specific test for detecting leaks at the cervical anastomotic site after esophagectomy.

Indexed as

Anastomotic leakBariumEsophagectomyEsophagus

Identifiers

PMID27066433
PMCPMC4825910
OpenAlexW2318356715

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.