Evidence map›Paper›PMID 27066170›Full record

ArticleCommunicative & integrative biology

Prevention of copper-induced cell death by GC-rich DNA oligomers in murine macrophage-like RAW264.7 cells.

Sakiko Matsushita, Shinichi Mochizuki, Kazuo Sakurai, Tomonori Kawano

Open access · goldAbstract read
In one paragraph

Article in Communicative & integrative biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sakiko MatsushitaFaculty and Graduate School of Environmental Engineering; The University of Kitakyushu ; Kitakyushu, Japan.
Shinichi MochizukiFaculty and Graduate School of Environmental Engineering; The University of Kitakyushu ; Kitakyushu, Japan.
Kazuo SakuraiFaculty and Graduate School of Environmental Engineering; The University of Kitakyushu ; Kitakyushu, Japan.
Tomonori KawanoFaculty and Graduate School of Environmental Engineering; The University of Kitakyushu ; Kitakyushu, Japan.
The University of Kitakyushu · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impact of redox active transition metals on activation of cell death signaling in plant cells have been documented to date. We have recently reported that GC-rich DNA oligomers with high affinity for binding of copper and catalytic activity for removal of ROS as novel plant cell-protecting agents. Here, we show that similar DNA oligomers protect the mouse macrophage-like RAW264.7 cells from copper-induced cell death, suggesting that the phenomenon firstly observed in plant model can be expanded to a wider range of cells and/or organisms including mammalian cells.

Indexed as

cell deathDNA oligomersmammalian cellsmetal toxicityplant cellsROS

Identifiers

PMID27066170
PMCPMC4802767
OpenAlexW2144360612

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.