Evidence map›Paper›PMID 27065974›Full record

ReviewFrontiers in microbiology2016

Proteomics As a Tool for Studying Bacterial Virulence and Antimicrobial Resistance.

Francisco J Pérez-Llarena, Germán Bou

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 115 citations in OpenAlex.

  1. Bacterial stress responses lower mRNA-protein level correlations.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  7. Article
  8. Proteomic Analysis of the Differential Response ofAntibiotics (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Proteomic landscape of imipenem resistance inFrontiers in cellular and infection microbiology · 2025
    Article
  14. Article
  15. Review
  16. Label-Free Quantitative Proteomics of Oral Microbial Communities.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Francisco J Pérez-LlarenaServicio de Microbiología-INIBIC, Complejo Hospitalario Universitario A Coruña A Coruña, Spain.
Germán BouServicio de Microbiología-INIBIC, Complejo Hospitalario Universitario A Coruña A Coruña, Spain.
Complexo Hospitalario Universitario A Coruña · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteomic studies have improved our understanding of the microbial world. The most recent advances in this field have helped us to explore aspects beyond genomics. For example, by studying proteins and their regulation, researchers now understand how some pathogenic bacteria have adapted to the lethal actions of antibiotics. Proteomics has also advanced our knowledge of mechanisms of bacterial virulence and some important aspects of how bacteria interact with human cells and, thus, of the pathogenesis of infectious diseases. This review article addresses these issues in some of the most important human pathogens. It also reports some applications of Matrix-Assisted Laser Desorption/Ionization-Time-Of-Flight (MALDI-TOF) mass spectrometry that may be important for the diagnosis of bacterial resistance in clinical laboratories in the future. The reported advances will enable new diagnostic and therapeutic strategies to be developed in the fight against some of the most lethal bacteria affecting humans.

Indexed as

antibioticbacteriadiagnosticproteomicsresistancevirulence

Identifiers

PMID27065974
PMCPMC4814472
OpenAlexW2328787315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.