Evidence map›Paper›PMID 27065751›Full record

ArticleEuropean journal of organic chemistry2015

A Mild and General One-Pot Synthesis of Densely Functionalized Diaryliodonium Salts.

Linlin Qin, Bao Hu, Kiel D Neumann, Ethan J Linstad, Katelyenn McCauley, Jordan Veness, Jayson J Kempinger, Stephen G DiMagno

Abstract read
In one paragraph

Article in European journal of organic chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. SJACS Au · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Site-selective aromatic C-H λChemical science · 2020
    Article
  6. Article
  7. One-Step Synthesis ofMolecules (Basel, Switzerland) · 2019
    Article
  8. FacileNature protocols · 2019
    Article
  9. Hypervalent aryliodine compounds as precursors for radiofluorination.Journal of labelled compounds & radiopharmaceuticals · 2018
    Review
  10. Flow Synthesis of Diaryliodonium Triflates.The Journal of organic chemistry · 2017
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linlin QinDepartment of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
Bao HuDepartment of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group; Institute of Industrial Catalysis, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014 (China).
Kiel D NeumannDepartment of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
Ethan J LinstadDepartment of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
Katelyenn McCauleyDepartment of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
Jordan VenessDepartment of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
Jayson J KempingerDepartment of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
Stephen G DiMagnoDepartment of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.

Funding

Synthesis of Radiofluorinated PET Imaging AgentsR01EB015536 · NIBIB · UNIVERSITY OF NEBRASKA LINCOLN · PI DIMAGNO, STEPHEN · 2012 to 2015
$1.2M
NIBIB NIH HHS R01 EB015536
6 · The paper itself

Abstract

Diaryliodonium salts are powerful and widely used arylating agents in organic chemistry. Here we report a scalable, synthesis of densely functionalized diaryliodonium salts from aryl iodides under mild conditions. This two-step, one-pot process has remarkable functional group tolerance, is compatible with commonly employed acid-labile protective group strategies, avoids heavy metal and transition metal reagents, and provides a direct route to stable precursors to PET imaging agents.

Indexed as

aryl iodidesdiaryliodonium saltsiodane synthesisoxidationSelectfluor™

Identifiers

PMID27065751
PMCPMC4824678

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.