ArticleBreast (Edinburgh, Scotland)2016
Hot flashes in breast cancer survivors: Frequency, severity and impact.
Article in Breast (Edinburgh, Scotland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Magnitude of placebo response in clinical trials of paroxetine for vasomotor symptoms: a meta-analysis.Frontiers in psychiatry · 2023Pooled it
- Comparing Interventions for Management of Hot Flashes in Patients With Breast and Prostate Cancer: A Systematic Review With Meta-Analyses.Oncology nursing forum · 2020Pooled it
- Efficacy of Low-Dose Paroxetine for the Treatment of Hot Flushes in Surgical and Physiological Postmenopausal Women: Systematic Review and Meta-Analysis of Randomized Trials.Medicina (Kaunas, Lithuania) · 2019Pooled it
- Survivorship, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.Journal of the National Comprehensive Cancer Network : JNCCN · 2017Guideline
- Impact of a Reproductive Health Survivorship Care Plan on Fertility, Pregnancy Concerns, and Accessing Reproductive Healthcare Among Young Nulliparous Breast Cancer Survivors.Cancer reports (Hoboken, N.J.) · 2026Trial
- Heart Rate Variability Biofeedback Training Can Improve Menopausal Symptoms and Psychological Well-Being in Women with a Diagnosis of Primary Breast Cancer: A Longitudinal Randomized Controlled Trial.Current oncology (Toronto, Ont.) · 2025Trial
- Comparative effectiveness of electro-acupuncture versus gabapentin for sleep disturbances in breast cancer survivors with hot flashes: a randomized trial.Menopause (New York, N.Y.) · 2017Trial
- The long road after breast cancer: survivorship issues and long-term treatment effects in young women.Frontiers in oncology · 2026Review
- Management of vasomotor symptoms in cancer patients.The oncologist · 2025Review
- Effects of menopause on temperature regulation.Temperature (Austin, Tex.) · 2025Review
- Acupuncture for fatigue in breast cancer survivors: a study protocol for a pragmatic, mixed method, randomised controlled trial.BMJ open · 2024Article
- Factors associated with insomnia symptoms over three years among premenopausal women with breast cancer.Breast cancer research and treatment · 2023Article
- Article
- Factors associated with the sleep disturbances of people with breast cancer during chemotherapy in China: A cross-sectional study.Nursing open · 2023Article
- Cross-cultural adaptation and psychometric properties of the Indonesian version for quality of life among breast cancer patients.Frontiers in public health · 2023Article
- Factors associated with worsening sexual function during adjuvant endocrine therapy in a prospective clinic-based cohort of women with early-stage breast cancer.Breast cancer research and treatment · 2022Article
- Association of treatment-emergent symptoms identified by patient-reported outcomes with adjuvant endocrine therapy discontinuation.NPJ breast cancer · 2022Article
- Environmental Stressors Suffered by Women with Gynecological Cancers in the Aftermath of Hurricanes Irma and María in Puerto Rico.International journal of environmental research and public health · 2021Article
- Thermoregulation is not impaired in breast cancer survivors during moderate-intensity exercise performed in warm and hot environments.Physiological reports · 2021Article
- Postmenopausal women in gynecological care.Przeglad menopauzalny = Menopause review · 2021Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
purposesTo (1) determine the frequency and severity of hot flashes, (2) examine the associations between hot flash frequency and severity and quality of life, and (3) identify the predictors of hot flash activity in breast cancer survivors.
methodsThe study used a cross-sectional design and mailed survey of 253 breast cancer survivors recruited from a cancer wellness clinic. Participants provided information regarding cancer history, hot flashes, pain intensity, sleep problems, physical functioning, and psychological functioning.
resultsAbout half of the survivors reported at least one hot flash in the past 24 h (45%) or past week (52%). The average frequency of hot flashes was 1.9 in the past 24 h and 1.8 in the past week. Hot flash severity was usually mild or asymptomatic. However, participants with hot flashes reported significantly more sleep problems and higher pain severity than those reporting no hot flashes. Moreover, the severity of hot flashes was associated with more sleep problems, higher pain severity, and more psychological dysfunction. History of hormonal suppression therapy and younger age predicted hot flash activity in the study sample.
conclusionsIn breast cancer survivors, hot flashes are common and are associated with unpleasant symptoms and poor quality of life. Research is needed to determine if treatments that reduce the frequency and severity of hot flashes in breast cancer survivors also result in improvements in symptoms such as sleep problems, pain, and psychological dysfunction.
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