ArticleFrontiers in aging neuroscience2016
Cortical Thinning in Healthy Aging Correlates with Larger Motor-Evoked EEG Desynchronization.
Article in Frontiers in aging neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Age-dependent electroencephalogram alterations under remimazolam anesthesia.Korean journal of anesthesiology · 2026Observational
- Differences in scalp-to-cortex tissues across age groups, sexes and brain regions: Implications for neuroimaging and brain stimulation techniques.Neurobiology of aging · 2024Article
- Evidence from theta-burst stimulation that age-related de-differentiation of the hippocampal network is functional for episodic memory.Neurobiology of aging · 2022Article
- Understanding the Role of Sensorimotor Beta Oscillations.Frontiers in systems neuroscience · 2021Review
- Characteristics of Resting State EEG Power in 80+-Year-Olds of Different Cognitive Status.Frontiers in aging neuroscience · 2021Article
- Association between Cerebral Oxygen Saturation with Outcome in Cardiac Surgery: Brain as an Index Organ.Journal of clinical medicine · 2020Article
- Older adults exhibit a more pronounced modulation of beta oscillations when performing sustained and dynamic handgrips.NeuroImage · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
Although electroencephalography (EEG) is a valuable tool to investigate neural activity in patients and controls, exactly how local anatomy impacts the measured signal remains unclear. Better characterizing this relationship is important to improve the understanding of how inter-subject differences in the EEG signal are related to neural activity. We hypothesized that cortical structure might affect event-related desynchronization (ERD) in EEG. Since aging is a well-documented cause of cortical thinning, we investigated the effects of cortical thickness (CT) and cortical depth (CD - the skull-to-cortex distance) on ERD using anatomical MRI and motor-evoked EEG in 17 healthy young adults and 20 healthy older persons. Results showed a significant negative correlation between ERD and CT, but no consistent relationship between ERD and CD. A thinner cortex was associated with a larger ERD in the α/β band and correcting for CT removed most of the inter-group difference in ERD. This indicates that differences in neural activity might not be the primary cause for the observed aging-related differences in ERD, at least in the motor cortex. Further, it emphasizes the importance of considering conditions affecting the EEG signal, such as cortical anatomical changes due to aging, when interpreting differences between healthy controls and/or patients.
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