Evidence map›Paper›PMID 27064746›Full record

ArticleAnnals of gastroenterology

Clinical practice guidelines for the surgical treatment of rectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO).

Evaghelos Xynos, Paris Tekkis, Nikolaos Gouvas, Louiza Vini, Evangelia Chrysou, Maria Tzardi, Vassilis Vassiliou, Ioannis Boukovinas, Christos Agalianos, Nikolaos Androulakis and 21 more

Abstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Evaghelos XynosGeneral Surgery, InterClinic Hospital of Heraklion, Greece (Evangelos Xynos).
Paris TekkisColorectal Surgery, Chelsea and Westminster NHS Foundation Trust, London, UK (Paris Tekkis, Panagiotis Georgiou).
Nikolaos GouvasGeneral Surgery, Metropolitan Hospital of Piraeus, Greece (Nikolaos Gouvas).
Louiza ViniRadiation Oncology, Iatriko Center of Athens, Greece (Louza Vini).
Evangelia ChrysouRadiology, University Hospital of Heraklion, Greece (Evangelia Chrysou).
Maria TzardiPathology, University Hospital of Heraklion, Greece (Maria Tzardi).
Vassilis VassiliouRadiation Oncology, Oncology Center of Bank of Cyprus, Nicosia, Cyprus (Vassilis Vassiliou).
Ioannis BoukovinasMedical Oncology, Bioclinic of Thessaloniki, Greece (Ioannis Boukovinas).
Christos AgalianosGeneral Surgery, Athens Naval & Veterans Hospital, Greece (Christos Agalianos, George Pechlivanides).
Nikolaos AndroulakisMedical Oncology, Venizeleion Hospital of Heraklion, Greece (Nikolaos Androulakis).
Athanasios AthanasiadisMedical Oncology, Koutlibaneion Hospital of Larissa, Greece (Athanasios Athanasiadis).
Christos ChristodoulouMedical Oncology, Metropolitan Hospital of Piraeus, Greece (Christos Christodoulou).
Christos DervenisGeneral Surgery, Konstantopouleio Hospital of Athens, Greece (Christos Dervenis).
Christos EmmanouilidisMedical Oncology, Interbalkan Medical Center, Thessaloniki, Greece (Christos Emmanouilidis).
Panagiotis GeorgiouColorectal Surgery, Chelsea and Westminster NHS Foundation Trust, London, UK (Paris Tekkis, Panagiotis Georgiou).
Ourania KatopodiMedical Oncology, Iaso General Hospital, Athens, Greece (Ourania Katopodi).
Panteleimon KountourakisMedical Oncology, Oncology Center of Bank of Cyprus, Nicosia, Cyprus (Panteleimon Kountourakis, Demetris Papamichael).
Thomas MakatsorisMedical Oncology, University Hospital of Patras, Greece (Thomas Makatsoris).
Pavlos PapakostasMedical Oncology, Ippokrateion Hospital of Athens, Greece (Pavlos Papakostas).
Demetris PapamichaelMedical Oncology, Oncology Center of Bank of Cyprus, Nicosia, Cyprus (Panteleimon Kountourakis, Demetris Papamichael).
George PechlivanidesGeneral Surgery, Athens Naval & Veterans Hospital, Greece (Christos Agalianos, George Pechlivanides).
Georgios PentheroudakisMedical Oncology, University Hospital of Ioannina, Greece (Georgios Pentheroudakis).
Ioannis PilpilidisGastroenterology, Theageneion Cancer Hospital, Thessaloniki, Greece (Ioannis Pilpilidis).
Joseph SgourosMedical Oncology, Agioi Anargyroi Hospital of Athens, Greece (Joseph Sgouros).
Charina TriantopoulouRadiology, Konstantopouleio Hospital of Athens, Greece (Charina Triantopoulou).
Spyridon XynogalosMedical Oncology, George Gennimatas General Hospital, Athens, Greece (Spyridon Xynogalos).
Niki KarachaliouMedical Oncology, Dexeus University Institute, Barcelona, Spain (Niki Karachaliou).
Nikolaos ZirasMedical Oncology, Metaxas Cancer Hospital, Piraeus, Greece (Nikolaos Ziras).
Odysseas ZorasGeneral Surgery, University Hospital of Heraklion, Greece (Odysseas Zoras).
John SouglakosMedical Oncology, University Hospital of Heraklion, Greece (John Souglakos).
[the Executive Team on behalf of the Hellenic Society of Medical Oncologists (HeSMO)]

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In rectal cancer management, accurate staging by magnetic resonance imaging, neo-adjuvant treatment with the use of radiotherapy, and total mesorectal excision have resulted in remarkable improvement in the oncological outcomes. However, there is substantial discrepancy in the therapeutic approach and failure to adhere to international guidelines among different Greek-Cypriot hospitals. The present guidelines aim to aid the multidisciplinary management of rectal cancer, considering both the local special characteristics of our healthcare system and the international relevant agreements (ESMO, EURECCA). Following background discussion and online communication sessions for feedback among the members of an executive team, a consensus rectal cancer management was obtained. Statements were subjected to the Delphi methodology voting system on two rounds to achieve further consensus by invited multidisciplinary international experts on colorectal cancer. Statements were considered of high, moderate or low consensus if they were voted by ≥80%, 60-80%, or <60%, respectively; those obtaining a low consensus level after both voting rounds were rejected. One hundred and two statements were developed and voted by 100 experts. The mean rate of abstention per statement was 12.5% (range: 2-45%). In the end of the process, all statements achieved a high consensus. Guidelines and algorithms of diagnosis and treatment were proposed. The importance of centralization, care by a multidisciplinary team, adherence to guidelines, and personalization is emphasized.

Indexed as

consensusDelphiGuidelinesrectal cancersurgical treatment

Identifiers

PMID27064746
PMCPMC4805730

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.