ArticleJournal of breast cancer2016
Oncologic Safety of Immediate Breast Reconstruction for Invasive Breast Cancer Patients: A Matched Case Control Study.
Article in Journal of breast cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- The Japanese Breast Cancer Society Clinical Practice Guidelines for surgical treatment of breast cancer, 2022 edition.Breast cancer (Tokyo, Japan) · 2024Guideline
- Skin-sparing mastectomy for the treatment of breast cancer.The Cochrane database of systematic reviews · 2023Pooled it
- Pooled it
- Long-term outcomes of skin-sparing mastectomy and nipple-sparing mastectomy versus traditional mastectomy in breast cancer: a case-control study based on preoperative ultrasound and clinical indicators.World journal of surgical oncology · 2025Article
- Outcomes of Deep Inferior Epigastric Artery Perforator (DIEP) Flap in Indian Population-A Prospective Single-Institute Study.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2024Article
- Incidence and risk factors for psychological distress in adult female patients with breast cancer: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Review
- Novel nomograms for predicting survival for immediate breast reconstruction patients diagnosed with invasive breast cancer-a single-center 15-year experience.Frontiers in oncology · 2023Article
- A Single-Center Retrospective Analysis of Local and Distant Relapse of Breast Cancer Following Immediate Breast Reconstruction According to Molecular Subtypes.Frontiers in oncology · 2022Article
- Useful Reduction Mammoplasty Technique in Oncoplastic Breast Surgery and Reconstruction.The breast journal · 2022Article
- Comparison of outcomes between immediate implantbased and autologous reconstruction: 15-year, single-center experience in a propensity score-matched Chinese cohort.Cancer biology & medicine · 2021Article
- Changes in Korean National Healthcare Insurance Policy and Breast Cancer Surgery Trend in Korea.Journal of Korean medical science · 2021Article
- Axillary lymph node recurrence in patients with breast cancer who underwent breast reconstruction using a latissimus dorsi flap after mastectomy.Molecular and clinical oncology · 2021Article
- A Retrospective Study of Latissimus Dorsi Flap in Immediate Breast Reconstruction.Frontiers in oncology · 2021Article
- Immediate versus secondary DIEP flap breast reconstruction: a multicenter outcome study.Archives of gynecology and obstetrics · 2020Article
- Oncologic outcomes after immediate breast reconstruction following mastectomy: comparison of implant and flap using propensity score matching.BMC cancer · 2020Article
- The Association Between Illness Acceptance and Quality of Life in Women with Breast Cancer.Cancer management and research · 2020Article
- Effectiveness and Safety of Implant-Based Breast Reconstruction in Locally Advanced Breast Carcinoma: A Matched Case-Control Study.Breast care (Basel, Switzerland) · 2019Article
- Body mass index and nipple preservation are major contributors to satisfaction and aesthetic outcome rates after implant-based immediate breast reconstruction.Contemporary oncology (Poznan, Poland) · 2019Article
- Postoperative outcomes of breast reconstruction after mastectomy: A retrospective study.Medicine · 2018Observational
- How to optimize aesthetic outcomes in implant-based breast reconstruction.Archives of plastic surgery · 2018Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to compare locoregional recurrence-free survival (LRFS) and disease-free survival (DFS) between patients undergoing mastectomy and immediate breast reconstruction (IBR) and those undergoing mastectomy alone.
methodsA retrospective review of patients who underwent mastectomy and immediate breast reconstruction for resectable invasive breast cancer between 2002 and 2010 at a single center was conducted. These cases were matched to patients who underwent mastectomy alone in the same time period, performed by 1:2 matching. Matching control variables included age, tumor size, axillary lymph node metastasis, and estrogen receptor status. Overall, 189 patients were identified in the IBR group, and 362 patients were matched to this group.
resultsIn the IBR group, 75 patients (39.7%) underwent conventional total mastectomy, 78 (41.3%) underwent skin-sparing mastectomy (SSM), and 36 (19.0%) underwent nipple-sparing mastectomy (NSM). The IBR group was significantly younger than the control group (41.9 and 45.1 years, respectively) (p=0.032), in spite of matching between three age groups. The DFS rates were similar between the IBR group and mastectomy alone group, at 92.0% and 89.9%, respectively, at 5-year follow-up (log-rank test, p=0.496). The 5-year LRFS was 96.2% in the IBR group and 96.4% in the mastectomy alone group (log-rank test, p=0.704), similar to data from previous reports. Subgroup analyses for SSM or NSM patients showed no differences in LRFS and DFS between the two groups. Additionally, in stage III patients, IBR did not cause an increase in recurrence.
conclusionIBR after mastectomy, including both SSM and NSM, had no negative impact on recurrence or patient survival, even in patients with advanced disease.
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