Evidence map›Paper›PMID 27064430›Full record

ArticleMuscle & nerve2016

A population-based survey of risk for cancer in individuals diagnosed with myotonic dystrophy.

Diana Abbott, Nicholas E Johnson, Lisa A Cannon-Albright

Open access · greenAbstract read
In one paragraph

Article in Muscle & nerve, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Myotonic dystrophy type 1 in South Korea: a comprehensive analysis of cancer and comorbidity risks.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
  7. Article
  8. Cancer and Myotonic Dystrophy.Journal of clinical medicine · 2023
    Review
  9. Targeting Myotonic Dystrophy Type 1 with Metformin.International journal of molecular sciences · 2022
    Review
  10. The Duchenne muscular dystrophy gene and cancer.Cellular oncology (Dordrecht, Netherlands) · 2021
    Review
  11. Article
  12. Article
  13. Benign tumors in myotonic dystrophy type I target disease-related cancer sites.Annals of clinical and translational neurology · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Diana AbbottDivision of Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA. diana.abbott@utah.edu.
Nicholas E JohnsonDepartment of Neurology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Lisa A Cannon-AlbrightDivision of Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.
University of Utah · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jared P Rutter · 1986 to 2026
$72.6M
Health Endpoints and Longitudinal Progression in Congenital Myotonic Dystrophy (HELP-CDM)K23NS091511 · NINDS · VIRGINIA COMMONWEALTH UNIVERSITY · PI JOHNSON, NICHOLAS ELWOOD · 2015 to 2019
$997k
NCI NIH HHS HHSN261201000026CNCI NIH HHS P30 CA042014NINDS NIH HHS K23 NS091511
6 · The paper itself

Abstract

introductionThe risk of cancer in patients diagnosed with myotonic dystrophy (DM) is reported for the homogeneous Utah population.

methodsClinical data accessed from the largest Utah healthcare providers have been record-linked to the Utah Population Database, a population-based resource also linked to the Utah Cancer Registry. Relative risks were estimated for 36 cancers of different types in 281 DM patients.

resultsTesticular cancer (relative risk [RR] = 10.74; 95% confidence interval [CI], 1.91-38.79), endometrial cancer (RR = 6.98; 95% CI, 1.24-25.22), and non-Hodgkin lymphoma (RR = 4.25; 95% CI, 1.16-12.43) were all observed at significant excess in DM patients.

conclusionsThis study confirms an overall increased risk of cancer in DM. Individuals diagnosed with DM might benefit from risk counseling. Muscle Nerve 54: 783-785, 2016.

Indexed as

Population SurveillanceSurveys and QuestionnairesEndometrial NeoplasmsFemaleHumansLymphoma, Non-HodgkinMaleMyotonic DystrophyNeoplasmsRisk FactorsTesticular NeoplasmsUtahcancermyotonic dystrophyneuromuscular diseaserelative riskUPDB

Identifiers

PMID27064430
PMCPMC5824717
OpenAlexW2339671091

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.