Evidence map›Paper›PMID 27064274›Full record

Trial reportPloS one2016

Effect and Process Evaluation of a Cluster Randomized Control Trial on Water Intake and Beverage Consumption in Preschoolers from Six European Countries: The ToyBox-Study.

An-Sofie Pinket, Wendy Van Lippevelde, Ilse De Bourdeaudhuij, Benedicte Deforche, Greet Cardon, Odysseas Androutsos, Berthold Koletzko, Luis A Moreno, Piotr Socha, Violeta Iotova and 3 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05140070 (Development and Implementation of an Innovative Technology for the Production New Generation Fruit and Vegetable Products Enriched With Dietary Fibre Preparation From Potato Starch With Prebiotic Properties for Children and Youth), which is not on this map. Cited by 28 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 7 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05140070 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Development and Implementation of an Innovative Technology for the Production New Generation Fruit and Vegetable Products Enriched With Dietary Fibre Preparation From Potato Starch With Prebiotic Properties for Children and Youth

TypeinterventionalSponsorChildren's Memorial Health Institute, PolandRan2021 to 2023Enrolled100ConditionsOverweight and Obesity, Child Obesity, Hypertension, NAFLDArmsVegetable and fruit mousse enriched with a fiber preparation from potato starch with prebiotic properties, Vegetable and fruit mousse, Dietary and physical activity counselling
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 7 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Interventions to prevent obesity in children aged 2 to 4 years old.The Cochrane database of systematic reviews · 2025
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  4. Interventions to increase the consumption of water among children: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020
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  6. Interventions for preventing obesity in children.The Cochrane database of systematic reviews · 2019
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  18. From preschool to policy: A scoping review of recommended interventions for a systems approach to improve dietary intake in early childhood.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 6 countries.

An-Sofie PinketDepartment of Public Health, Ghent University, Ghent, Belgium.
Wendy Van LippeveldeDepartment of Public Health, Ghent University, Ghent, Belgium.
Ilse De BourdeaudhuijDepartment of Movement and Sport Sciences, Ghent University, Ghent, Belgium.
Benedicte DeforcheDepartment of Public Health, Ghent University, Ghent, Belgium.
Greet CardonDepartment of Movement and Sport Sciences, Ghent University, Ghent, Belgium.
Odysseas AndroutsosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Berthold KoletzkoLudwig-Maximilians-University of Munich, Dr. von Hauner Children's Hospital, München, Germany.
Luis A MorenoGENUD (Growth, Exercise, NUtrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain.
Piotr SochaThe Children's Memorial Health Institute, Warsaw, Poland.
Violeta IotovaDept. of pediatrics and medical Genetics, Medical University of Varna, Varna, Bulgaria.
Yannis ManiosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Marieke De CraemerDepartment of Movement and Sport Sciences, Ghent University, Ghent, Belgium.
ToyBox-Study Group
Ghent University · BEHarokopio University of Athens · GRChildren's Memorial Health Institute · PLLudwig-Maximilians-Universität München · DEMedical University of Varna · BGUniversidad de Zaragoza · ES

Funding

Medical Research Council MR/K02325X/1
6 · The paper itself

Abstract

backgroundWithin the ToyBox-study, a kindergarten-based, family-involved intervention was developed to prevent overweight and obesity in European preschoolers, targeting four key behaviours related to early childhood obesity, including water consumption. The present study aimed to examine the effect of the ToyBox-intervention (cluster randomized controlled trial) on water intake and beverage consumption in European preschoolers and to investigate if the intervention effects differed by implementation score of kindergartens and parents/caregivers.

methodA sample of 4964 preschoolers (4.7 ± 0.4 years; 51.5% boys) from six European countries (Belgium, Bulgaria, Germany, Greece, Poland, Spain) was included in the data analyses. A standardized protocol was used and parents/caregivers filled in socio-demographic data and a food-frequency questionnaire. To assess intervention effects, multilevel repeated measures analyses were conducted for the total sample and for the six country-specific samples. Based on the process evaluation questionnaire of teachers and parents/caregivers, an implementation score was constructed. To assess differences in water intake and beverage consumption by implementation score in the total sample, multilevel repeated measures analyses were performed.

resultsLimited intervention effects on water intake from beverages and overall beverage consumption were found. However, important results were found on prepacked fruit juice consumption, with a larger decrease in the intervention group compared to the control group. However, also a decline in plain milk consumption was found. Implementation scores were rather low in both kindergartens and parents/caregivers. Nevertheless, more favorable effects on beverage choices were found in preschoolers whose parents/caregivers and kindergarten teachers had higher implementation scores compared to those with lower implementation scores.

conclusionThe ToyBox-intervention can provide the basis for the development of more tailor-made interventions. However, new strategies to improve implementation of interventions should be created.

Indexed as

DrinkingHealth BehaviorHealth Knowledge, Attitudes, PracticeProgram EvaluationBeveragesChild, PreschoolEuropeFacultyFemaleHumansMaleParentsPediatric ObesitySchoolsSedentary BehaviorSurveys and Questionnaires

Identifiers

PMID27064274
PMCPMC4827861
OpenAlexW2334621394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.