Evidence map›Paper›PMID 27064212›Full record

ReviewCurrent opinion in cell biology2016

Finding a place in the SUN: telomere maintenance in a diverse nuclear landscape.

Hani Ebrahimi, Julia Promisel Cooper

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hani EbrahimiTelomere Biology Section, LBMB, NCI, NIH, Bethesda, MD 20892, USA.
Julia Promisel CooperTelomere Biology Section, LBMB, NCI, NIH, Bethesda, MD 20892, USA. Electronic address: julie.cooper@nih.gov.

Funding

Telomere BiologyZIABC011519 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI COOPER, JULIA · 2013 to 2020
$13.1M
Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA BC011519
6 · The paper itself

Abstract

Telomeres function in the context of a complex nuclear milieu in which telomeres tend to occupy distinct subnuclear regions. Indeed, regulation of the subnuclear positioning of telomeres is conserved from yeast to human, raising the age-old question: to what extent is location important for function? In mitotically dividing cells, the positioning of telomeres affects their epigenetic state and influences telomere processing and synthesis. In meiotic cells, telomere location is important for homologue pairing, centromere assembly and spindle formation. Here we focus on recent insights into the functions of telomere positioning in maintaining genome integrity.

Indexed as

AnimalsCell NucleusChromosomesEukaryotic CellsHumansNuclear EnvelopeTelomere

Identifiers

PMID27064212
PMCPMC6284805

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.