Evidence map›Paper›PMID 27063468›Full record

ArticleCellular & molecular immunology2017

Trap1a is an X-linked and cell-intrinsic regulator of thymocyte development.

Chi-Shan Li, Fei Tang, Peng Zhang, Taijiao Jiang, Thomas L Saunders, Pan Zheng, Yang Liu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular & molecular immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Negative Regulation of the Differentiation of Flk2International journal of molecular sciences · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Chi-Shan LiInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, China.
Fei TangCenter for Cancer and Immunology Research, Children's National Medical Center, Washington, DC, USA.
Peng ZhangInstitute of Biophysics, Chinese Academy of Science, Beijing, China.
Taijiao JiangInstitute of Biophysics, Chinese Academy of Science, Beijing, China.
Thomas L SaundersDepartment of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, MI, USA.
Pan ZhengCenter for Cancer and Immunology Research, Children's National Medical Center, Washington, DC, USA.
Yang LiuCenter for Cancer and Immunology Research, Children's National Medical Center, Washington, DC, USA.
Children's National · USInstitute of Biophysics · CNInstitute of Biomedical Sciences, Academia Sinica · TWUniversity of Michigan–Ann Arbor · US

Funding

Checkpoints of Host Response to Cellular InjuriesR01AI064350 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, YANG, ZHENG, PAN · 2006 to 2019
$5.6M
Tumor burden and T cell immunityR01CA058033 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, YANG · 1992 to 2013
$3.3M
Targeted Elimination of Cancer Stem Cells for AML TherapyR01CA171972 · NCI · CHILDREN'S RESEARCH INSTITUTE · PI LIU, YANG, MALEK, SAMI NIMER · 2013 to 2017
$2.3M
mTOR, Inflammation and Senescence of Hematopoietic Stem CellsR01AG036690 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZHENG, PAN · 2010 to 2014
$1.6M
NCI NIH HHS R01 CA058033NCI NIH HHS R01 CA171972NIAID NIH HHS R01 AI064350NIA NIH HHS R01 AG036690
6 · The paper itself

Abstract

The X-linked Trap1a gene encodes the tumor rejection antigen P1A, which is expressed in fetal tissues and multiple lineages of tumor cells. The function of this gene remains unknown. Using chimeric mice with wild-type (WT) and Trap1a

Indexed as

AnimalsAntigens, NeoplasmBone Marrow CellsBone Marrow TransplantationCell DifferentiationGenes, X-LinkedMiceMice, Inbred C57BLMice, KnockoutProto-Oncogene Proteins c-kitReceptor, Notch1Signal TransductionThymocytesT-LymphocytesTransplantation ChimeraAntigens, Neoplasmcancer-testis antigen P1A, mouseNotch1 protein, mouseProto-Oncogene Proteins c-kitReceptor, Notch1

Identifiers

PMID27063468
PMCPMC5549601
OpenAlexW2328017512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.