Evidence map›Paper›PMID 27062452›Full record

ArticleSocial science & medicine (1982)2016

Marital disruption is associated with shorter salivary telomere length in a probability sample of older adults.

Mark A Whisman, Briana L Robustelli, David A Sbarra

Abstract read
In one paragraph

Article in Social science & medicine (1982), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  6. Review
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  11. Marriage, divorce, and the immune system.The American psychologist · 2018
    Review
  12. Article
  13. Article
  14. Evaluating minimally invasive sample collection methods for telomere length measurement.American journal of human biology : the official journal of the Human Biology Council · 2018
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mark A WhismanUniversity of Colorado Boulder, USA. Electronic address: mark.whisman@colorado.edu.
Briana L RobustelliUniversity of Colorado Boulder, USA.
David A SbarraUniversity of Arizona, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Gene-by-Environment Interactions, Social Stress, and Depression in Older AdultsR03AG045301 · NIA · UNIVERSITY OF COLORADO · PI WHISMAN, MARK A · 2013 to 2013
$76k
NIA NIH HHS R03 AG045301NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

rationaleMarital disruption (i.e., marital separation, divorce) is associated with a wide range of poor mental and physical health outcomes, including increased risk for all-cause mortality. One biological intermediary that may help explain the association between marital disruption and poor health is accelerated cellular aging.

objectiveThis study examines the association between marital disruption and salivary telomere length in a United States probability sample of adults ≥50 years of age.

methodParticipants were 3526 individuals who participated in the 2008 wave of the Health and Retirement Study. Telomere length assays were performed using quantitative real-time polymerase chain reaction (qPCR) on DNA extracted from saliva samples. Health and lifestyle factors, traumatic and stressful life events, and neuroticism were assessed via self-report. Linear regression analyses were conducted to examine the associations between predictor variables and salivary telomere length.

resultsBased on their marital status data in the 2006 wave, people who were separated or divorced had shorter salivary telomeres than people who were continuously married or had never been married, and the association between marital disruption and salivary telomere length was not moderated by gender or neuroticism. Furthermore, the association between marital disruption and salivary telomere length remained statistically significant after adjusting for demographic and socioeconomic variables, neuroticism, cigarette use, body mass, traumatic life events, and other stressful life events. Additionally, results revealed that currently married adults with a history of divorce evidenced shorter salivary telomeres than people who were continuously married or never married.

conclusionAccelerated cellular aging, as indexed by telomere shortening, may be one pathway through which marital disruption is associated with morbidity and mortality.

Indexed as

Family ConflictAgedBody Mass IndexCellular SenescenceCohort StudiesFemaleHumansMaleMarital StatusMiddle AgedNeuroticismPolymerase Chain ReactionSalivaSocial ClassStress, PsychologicalTelomereCellular agingDivorceMarital disruptionMarital separationTelomereUnited States

Identifiers

PMID27062452
PMCPMC4883574

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.