Evidence map›Paper›PMID 27062231›Full record

ArticleInternational journal for numerical methods in biomedical engineering2017

3D time-varying simulations of Ca

Constantine Zakkaroff, Stephen Moore, Stewart Dowding, Tim David

Open access · hybridAbstract read
In one paragraph

Article in International journal for numerical methods in biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. 3D time-varying simulations of CaInternational journal for numerical methods in biomedical engineering · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Constantine ZakkaroffUC HPC Centre, University of Canterbury, Christchurch, New Zealand.
Stephen MooreIBM Research Collaboratory for Life Sciences, Melbourne, Australia.
Stewart DowdingUC HPC Centre, University of Canterbury, Christchurch, New Zealand.
Tim DavidUC HPC Centre, University of Canterbury, Christchurch, New Zealand.
University of Canterbury · NZIBM Research - Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preferential locations of atherosclerotic plaque are strongly associated with the areas of low wall shear stress and disturbed haemodynamic characteristics such as flow detachment, flow recirculation and oscillatory flow. The areas of low wall shear stress are also associated with the reduced production of adenosine triphosphate in the endothelial layer, as well as the resulting reduced production of inositol trisphosphate (IP

Indexed as

ArteriesAtherosclerosisCalciumComputer SimulationEndothelial CellsHumansModels, BiologicalRheologyStress, MechanicalCalciumatherosclerosiscoupled arterial cellsendothelial cellsintercellular calcium waveslarge-scale physiological simulationsmooth muscle cells

Identifiers

PMID27062231
PMCPMC5298049
OpenAlexW2339775458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.