ArticlePhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)2016
The relationship between cancer detection in mammography and image quality measurements.
Article in Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 42 citations in OpenAlex.
- Landmark Regression with Attention U-Net for Assessing Breast Positioning Quality in MLO Mammography View.Diagnostics (Basel, Switzerland) · 2026Article
- Exploring the impact of image restoration in simulating higher dose mammography: effects on the detectability of microcalcifications across different sizes using model observer analysis.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Automated Software Evaluation in Screening Mammography: A Scoping Review of Image Quality and Technique Assessment.Current oncology (Toronto, Ont.) · 2025Article
- Predicting the quality of digital mammography from the perspective of detectability of microcalcifications: A Radiomics approach.Medical physics · 2025Article
- Quality assurance in Mammography: An overview.European journal of radiology · 2023Article
- Article
- Image Quality Comparison between Digital Breast Tomosynthesis Images and 2D Mammographic Images Using the CDMAM Test Object.Journal of imaging · 2022Article
- Validation of a mammographic image quality modification algorithm using 3D-printed breast phantoms.Journal of medical imaging (Bellingham, Wash.) · 2021Article
- On the relevance of modulation transfer function measurements in digital mammography quality control.Journal of medical imaging (Bellingham, Wash.) · 2021Article
- An investigation into the validity of utilising the CDRAD 2.0 phantom for optimisation studies in digital radiography.The British journal of radiology · 2018Article
- Quality assurance target for community-based breast cancer screening in China: a model simulation.BMC cancer · 2018Article
- A review of mammographic positioning image quality criteria for the craniocaudal projection.The British journal of radiology · 2018Review
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
purposeTo investigate the relationship between image quality measurements and the clinical performance of digital mammographic systems.
methodsMammograms containing subtle malignant non-calcification lesions and simulated malignant calcification clusters were adapted to appear as if acquired by four types of detector. Observers searched for suspicious lesions and gave these a malignancy score. Analysis was undertaken using jackknife alternative free-response receiver operating characteristics weighted figure of merit (FoM). Images of a CDMAM contrast-detail phantom were adapted to appear as if acquired using the same four detectors as the clinical images. The resultant threshold gold thicknesses were compared to the FoMs using a linear regression model and an F-test was used to find if the gradient of the relationship was significantly non-zero.
resultsThe detectors with the best image quality measurement also had the highest FoM values. The gradient of the inverse relationship between FoMs and threshold gold thickness for the 0.25mm diameter disk was significantly different from zero for calcification clusters (p=0.027), but not for non-calcification lesions (p=0.11). Systems performing just above the minimum image quality level set in the European Guidelines for Quality Assurance in Breast Cancer Screening and Diagnosis resulted in reduced cancer detection rates compared to systems performing at the achievable level.
conclusionsThe clinical effectiveness of mammography for the task of detecting calcification clusters was found to be linked to image quality assessment using the CDMAM phantom. The European Guidelines should be reviewed as the current minimum image quality standards may be too low.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.