ArticleJournal of clinical laboratory analysis2016
Reference Intervals of Routine Coagulation Assays During the Pregnancy and Puerperium Period.
Article in Journal of clinical laboratory analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Clinical Study to Define Precision, Accuracy, and Comparability of Results From a Novel Point of Care Fibrinogen Assay (F-Point), Compared to an Industry Standard
Establishment of Reference Intervals of Complete Blood Count and Coagulation Tests in Pregnant Women at Hung Vuong Hospital
Who cites it
17 citing papers in PubMed.
- Baseline values for QuantraBMC pregnancy and childbirth · 2025Observational
- Proteomic Profiles of Maternal Plasma Extracellular Vesicles for Prediction of Preeclampsia.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024Article
- Article
- Reference intervals of complete blood count and coagulation tests in Vietnamese pregnant women.BMC pregnancy and childbirth · 2023Article
- Trimester-specific reference intervals and profile of coagulation parameters for Chinese pregnant women with diverse demographics and obstetric history: a cross-sectional study.BMC pregnancy and childbirth · 2023Article
- Specific changes and clinical significance of plasma D-dimer during pregnancy and puerperium: a prospective study.BMC pregnancy and childbirth · 2023Article
- Laboratory Testing of Hemostasis in Pregnancy: A Brief Overview.Methods in molecular biology (Clifton, N.J.) · 2023Review
- [Clinical Confusion Concerning Increased D-Dimer Value during Pregnancy].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022Review
- Changes of new coagulation markers in healthy pregnant women and establishment of reference intervals in Changsha.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022Article
- Reference intervals for coagulation parameters in non-pregnant and pregnant women.Scientific reports · 2022Article
- The interrelationship between pregnancy, venous thromboembolism, and thyroid disease: a hypothesis-generating review.Thyroid research · 2021Review
- Changes in levels of coagulation parameters in different trimesters among Chinese pregnant women.Journal of clinical laboratory analysis · 2021Article
- Reference Values of D-Dimers and Fibrinogen in the Course of Physiological Pregnancy: the Potential Impact of Selected Risk Factors-A Pilot Study.BioMed research international · 2020Article
- To Clot or Not: HELLP Syndrome and Disseminated Intravascular Coagulation in an Eclamptic Patient with Intrauterine Fetal Demise.Case reports in anesthesiology · 2020Article
- Changes in biochemical tests in pregnancy and their clinical significance.Obstetric medicine · 2018Review
- Physiological changes of pregnancy and the Swansea criteria in diagnosing acute fatty liver of pregnancy.Obstetric medicine · 2018Article
- Establishment Trimester-Specific Reference Intervals of Anticoagulation and Fibrinolysis Indicators in Healthy Pregnant Women in Beijing, China.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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3 authors.
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Abstract
backgroundSignificant changes occur in the coagulation and fibrinolytic systems during pregnancy and puerperium in the plasma levels. However, reference ranges based on healthy people are not optimal for informing clinical decisions during the pregnancy and puerperium. Therefore, it is essential to explore coagulation assays' reference ranges during the pregnancy and puerperium.
methodsProthrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen (Fib.), and D-dimer were all measured according to the manufacturer's specifications and laboratory standard operating procedure of the STA-R evolution coagulation analyzer. A total of 11,601 women were enrolled in this study.
resultsThe reference ranges for PT, APTT, TT, Fib., and D-dimer in nonpregnancy period were 10.87-13.76 s, 29.22-44.61 s, 15.39-20.15 s, 1.59-3.97 g/l, and 0-0.56 mg/l, respectively. In early-pregnancy period, the ranges were 11.14-14.07 s, 29.97-44.69 s, 14.92-19.03 s, 1.98-4.13 g/l, and 0-1.67 mg/l, respectively. In midpregnancy period, the ranges were 9.98-12.84 s, 28.53-40.70 s, 13.51-19.82 s, 2.63-5.19 g/l, and 0-2.81 mg/l, respectively. In late-pregnancy period, the ranges were 9.48-12.58 s, 28.61-40.80 s, 14.10-19.61 s, 2.80-5.56 g/l, and 0-27.08 mg/l, respectively. In puerperium period, the ranges were 10.85-13.72 s, 30.51-43.02 s, 15.31-19.64 s, 1.14-5.07 g/l, and 1.27-4.85 mg/l, respectively.
conclusionWe presented reference intervals for coagulation assays from the nonpregnancy to puerperium period that can be adopted in other laboratories after further validation.
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