Evidence map›Paper›PMID 27061734›Full record

ReviewCurrent genetics2016

Condensin-mediated chromosome organization in fission yeast.

Osamu Iwasaki, Ken-Ichi Noma

Abstract readReview
In one paragraph

Review in Current genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. New insights into cohesin loading.Current genetics · 2018
    Review
  10. Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Osamu IwasakiGene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA, 19104, USA.
Ken-Ichi NomaGene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA, 19104, USA. noma@wistar.org.

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Alessandro Gardini · 1985 to 2026
$75.9M
A New Methodology to Decipher Three-Dimensional Genome StructureDP2OD004348 · OD · WISTAR INSTITUTE · PI NOMA, KENICHI · 2008 to 2008
$3.1M
NCI NIH HHS P30 CA010815NIH HHS DP2 OD004348
6 · The paper itself

Abstract

Genome/chromosome structures are formed by a hierarchy of organizing processes ranging from gene interactions to chromosome territory formation. The SMC complex, cohesin, mediates interactions among enhancers and promoters, thereby regulating transcription. Another SMC complex, condensin, also plays critical roles in genome organization, although the detailed mechanisms remain much less well understood. Here, we discuss our recent findings on how fission yeast condensin mediates interactions among genes and how condensin-dependent interactions play dual roles in the chromosome territory arrangement during interphase and in mitotic chromosome organization, which supports the fidelity of chromosome segregation. Our studies suggest that condensin serves as a functional ligature connecting gene interactions, chromosome territory arrangement, transcriptional regulation, and chromosome segregation.

Indexed as

Adenosine TriphosphatasesChromosome SegregationChromosomes, FungalDNA-Binding ProteinsGene Expression Regulation, FungalMitosisMultiprotein ComplexesProtein BindingProtein TransportSchizosaccharomycesTATA-Box Binding ProteinTranscription, GeneticAdenosine Triphosphatasescondensin complexesDNA-Binding ProteinsMultiprotein ComplexesTATA-Box Binding Protein3D genome organizationChromosome segregationChromosome territoryCondensinFission yeastMitotic chromosome assembly

Identifiers

PMID27061734
PMCPMC5184768

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.