Evidence map›Paper›PMID 27061495›Full record

ArticleTrends in biochemical sciences2016

Lipid Rafts Assemble Dynein Ensembles.

Jeffrey J Nirschl, Amy E Ghiretti, Erika L F Holzbaur

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in biochemical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jeffrey J NirschlDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, 638A Clinical Research Building, 415 Curie Boulevard, PA 19104-6085, USA.
Amy E GhirettiDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, 638A Clinical Research Building, 415 Curie Boulevard, PA 19104-6085, USA.
Erika L F HolzbaurDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, 638A Clinical Research Building, 415 Curie Boulevard, PA 19104-6085, USA. Electronic address: holzbaur@mail.med.upenn.edu.
University of Pennsylvania · US

Funding

The Interaction of Cytoplasmic Dynein and DynactinR01GM048661 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI HOLZBAUR, ERIKA L · 1993 to 2017
$6.0M
Pathogenic Mechanisms of Reduced Transport Initiation in Perry SyndromeF30NS092227 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI NIRSCHL, JEFFREY JOHN · 2015 to 2017
$118k
Mechanisms of dendritic cargo trafficking and microtubule dynamic regulation by KIF21BF32MH108187 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GHIRETTI, AMY ELIZABETH · 2015 to 2016
$88k
NIGMS NIH HHS R01 GM048661NIMH NIH HHS F32 MH108187NINDS NIH HHS F30 NS092227
6 · The paper itself

Abstract

New work by Rai et al. identifies a novel mechanism regulating phagosome transport in cells: the clustering of dynein motors into lipid microdomains, leading to enhanced unidirectional motility. Clustering may be especially important for dynein, a motor that works most efficiently in teams.

Indexed as

AnimalsBiological TransportCell LineDyneinsGlycosphingolipidsKinesinsLeishmania donovaniMacrophagesMembrane FusionMembrane MicrodomainsMiceMicrotubulesPhagocytosisPhagosomesDyneinsGlycosphingolipidsKinesinslipophosphonoglycan

Identifiers

PMID27061495
PMCPMC4851571
OpenAlexW2332397240

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.