Evidence map›Paper›PMID 27061189›Full record

ArticleAllergy2017

Ontogeny of human IgE-expressing B cells and plasma cells.

F Ramadani, H Bowen, N Upton, P S Hobson, Y-C Chan, J-B Chen, T W Chang, J M McDonnell, B J Sutton, D J Fear and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Allergen-specific IgGThe Journal of allergy and clinical immunology · 2020
    Trial
  3. Article
  4. Article
  5. Review
  6. Whence and wherefore IgE?Immunological reviews · 2024
    Review
  7. Review
  8. Article
  9. B cell receptor ligation induces IgE plasma cell elimination.The Journal of experimental medicine · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. The Multifaceted B Cell Response in Allergen Immunotherapy.Current allergy and asthma reports · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

F RamadaniRandall Division of Cell and Molecular Biohphysics, King's College, London, UK.ORCID http://orcid.org/0000-0001-8228-4868
H BowenRandall Division of Cell and Molecular Biohphysics, King's College, London, UK.
N UptonRandall Division of Cell and Molecular Biohphysics, King's College, London, UK.
P S HobsonDivision of Asthma, Allergy and Lung Biology, King's College, London, UK.
Y-C ChanRandall Division of Cell and Molecular Biohphysics, King's College, London, UK.
J-B ChenGenomics Research Center, Academia Sinica, Taipei, Taiwan.
T W ChangGenomics Research Center, Academia Sinica, Taipei, Taiwan.
J M McDonnellRandall Division of Cell and Molecular Biohphysics, King's College, London, UK.
B J SuttonRandall Division of Cell and Molecular Biohphysics, King's College, London, UK.
D J FearDivision of Asthma, Allergy and Lung Biology, King's College, London, UK.
H J GouldRandall Division of Cell and Molecular Biohphysics, King's College, London, UK.
King's College London · GBGenomics Research Center, Academia Sinica · TW

Funding

Biotechnology and Biological Sciences Research Council BB/H019634/1Medical Research Council G0200486Medical Research Council G0400106Medical Research Council G0501494Medical Research Council G1000758Medical Research Council G1100090Medical Research Council G1100238Medical Research Council MR/M022943/1Wellcome Trust 076343
6 · The paper itself

Abstract

backgroundIgE-expressing (IgE

objectiveTo characterize the development pathway of human IgE

methodsTo generate human IgE

resultsWe have identified three phenotypic stages of IgE

conclusionGeneration of IgE

Indexed as

Gene ExpressionBiomarkersB-LymphocytesCell DifferentiationCells, CulturedGerminal CenterHumansImmunoglobulin Class SwitchingImmunoglobulin EImmunoglobulin GImmunophenotypingPhenotypePlasma CellsBiomarkersImmunoglobulin EImmunoglobulin Gallergygerminal centrehuman B cellsIgE class switchingplasma cell

Identifiers

PMID27061189
PMCPMC5107308
OpenAlexW2315359128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.