Evidence map›Paper›PMID 27061070›Full record

ArticleJournal of Parkinson's disease2016

Development and Validation of the Parkinson's Disease Medication Beliefs Scale (PD-Rx).

Jori E Fleisher, Nabila A Dahodwala, Sharon X Xie, Mark Mayo, Daniel Weintraub, Joshua Chodosh, Judy A Shea

Open access · greenAbstract readValidation Study
In one paragraph

Article in Journal of Parkinson's disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jori E FleisherThe Marlene and Paolo Fresco Institute for Parkinson's and Movement Disorders, New York University School of Medicine, Departments of Neurology and Population Health, New York, NY, USA.
Nabila A DahodwalaUniversity of Pennsylvania Perelman School of Medicine, Department of Neurology, Philadelphia, PA, USA.
Sharon X XieUniversity of Pennsylvania Perelman School of Medicine, Department of Biostatistics and Epidemiology., Philadelphia, PA, USA.
Mark MayoUniversity of Pennsylvania Perelman School of Medicine, Department of Neurology, Philadelphia, PA, USA.
Daniel WeintraubUniversity of Pennsylvania Perelman School of Medicine, Department of Neurology, Philadelphia, PA, USA.
Joshua ChodoshNew York University School of Medicine, Division of Geriatric Medicine and Palliative Care, Department of Medicine, New York, NY, USA.
Judy A SheaUniversity of Pennsylvania Perelman School of Medicine, Department of Medicine, Philadelphia, PA, USA.
University of Pennsylvania · USNew York University · US

Funding

PSYCHOSOCIAL COREP30AG008051 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WISNIEWSKI, THOMAS M · 1990 to 2019
$36.1M
Project IV: "Alpha-Synuclein Strains & Diverse Synucleinopathies"P50NS053488 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI TROJANOWSKI, JOHN Q. · 2007 to 2017
$20.9M
Neurologic Clinical Epidemiology Training ProgramT32NS061779 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Andrea Lauren Christman Schneider, Allison Willis · 2008 to 2026
$4.6M
Mechanisms of health disparities in parkinsonismK23AG034236 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAHODWALA, NABILA · 2010 to 2014
$793k
NIA NIH HHS K23 AG034236NIA NIH HHS P30 AG008051NINDS NIH HHS P50 NS053488NINDS NIH HHS T32 NS061779
6 · The paper itself

Abstract

backgroundMedication non-adherence is common in Parkinson's disease (PD) and is associated with increased disability and healthcare costs. Individuals' beliefs regarding their medical conditions and treatments impact medication adherence. While instruments exist to measure patients' beliefs about medications in general, no such tool exists for PD.

objectivesCreate an instrument eliciting medication beliefs of persons with PD; identify demographic and clinical characteristics associated with beliefs; and examine whether beliefs are associated with dopaminergic therapy adherence.

methodsWe developed the Parkinson's Disease Medication Beliefs Scale (PD-Rx) in four phases: focus groups of patients and caregivers to generate items, scale development, expert and patient revision of items, and a cross-sectional validation sample (n = 75). Adherence was calculated using two approaches incorporating self-reported medication lists.

resultsThe PD-Rx consists of 11 items covering benefits and risks of PD pharmacotherapies. The scale covers motor improvement, current adverse effects, and future concerns. Higher scores indicate more positive beliefs. Internal consistency was acceptable (Cronbach's alpha = 0.67). Test-retest reliability was 0.47. Quality of life was associated with PD-Rx scores, and lower scores were associated with non-adherence.

conclusionsNegative beliefs about PD treatments are associated with lower quality of life and may be related to medication non-adherence. Further study of any causal relationship between beliefs and medication non-adherence in PD will inform the design of future patient-centered interventions to improve adherence.

Indexed as

Health Knowledge, Attitudes, PracticeSurveys and QuestionnairesAgedAntiparkinson AgentsCross-Sectional StudiesFemaleHumansMaleMedication AdherenceMiddle AgedParkinson DiseasePsychometricsReproducibility of ResultsAntiparkinson Agentsadherencehealth belief modelParkinson’s diseasePatient beliefspsychometric

Identifiers

PMID27061070
PMCPMC4884139
OpenAlexW2336900477

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.